Genzyme Corp Sample Contracts

AMONG
Credit Agreement • March 30th, 2000 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
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INDENTURE
Indenture • March 3rd, 2000 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
LEASE
Lease Agreement • November 14th, 2000 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
Acquisition Proposal..........................................................35 Affiliates ....................................................................49 Agreemen t......................................................................1 Assign...
Merger Agreement • August 13th, 2003 • Genzyme Corp • Biological products, (no disgnostic substances) • Delaware

ERISA.........................................................................23 ERISA Affiliate...............................................................23 Exchange Act...................................................................2 Expiration Date................................................................2 FDA...........................................................................17 FDCA..........................................................................17 Fee Conversion Options.........................................................9 FTC...........................................................................38 Fully Diluted Shares..........................................................54 GAAP..........................................................................15 Governmental Entity...........................................................14 HSR Act.......................................................................14 Indemnified Liability.......

4,000,000 SHARES GENZYME CORPORATION GENZYME TISSUE REPAIR DIVISION COMMON STOCK UNDERWRITING AGREEMENT
Underwriting Agreement • October 30th, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
UNDERWRITING AGREEMENT
Underwriting Agreement • September 19th, 1995 • Genzyme Corp • Pharmaceutical preparations • New York
1 EXHIBIT 10.4 THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED UPON ITS EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON TRANSFER SET FORTH IN SECTION 4 OF THIS WARRANT
Common Stock Purchase Warrant • November 14th, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
GENZYME CORPORATION 3% CONVERTIBLE SUBORDINATED DEBENTURES DUE 2021 REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • May 11th, 2001 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
AMONG
Credit Agreement • March 31st, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
1 EXHIBIT 4.5 GENZYME CORPORATION 5 1/4% Convertible Subordinated Notes Due 2005 PURCHASE AGREEMENT
Purchase Agreement • July 21st, 1998 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
3,000,000 Shares GENZYME CORPORATION Genzyme Molecular Oncology Division Common Stock UNDERWRITING AGREEMENT ----------------------
Underwriting Agreement • June 8th, 1998 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
LEASE
Lease Agreement • November 14th, 2000 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
EXHIBIT A
Common Stock Purchase Agreement • July 18th, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
EXHIBIT 10.2
Lease • August 8th, 2005 • Genzyme Corp • Biological products, (no disgnostic substances)
Exhibit 2.1 AGREEMENT AND PLAN OF MERGER
Merger Agreement • February 27th, 2004 • Genzyme Corp • Biological products, (no disgnostic substances) • Delaware
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and American Stock Transfer & Trust Company, Rights Agent
Rights Agreement • June 11th, 1999 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
LEASE BETWEEN
Lease Agreement • August 14th, 2002 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
ii) 4 AMENDED AND RESTATED RIGHTS AGREEMENT
Rights Agreement • May 1st, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
GENZYME CORPORATION $500,000,000 3.625% Senior Notes Due 2015 $500,000,000 5.000% Senior Notes Due 2020 REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • June 17th, 2010 • Genzyme Corp • Biological products, (no disgnostic substances) • New York

Genzyme Corporation, a Massachusetts corporation (the “Company”), proposes to issue and sell, upon the terms set forth in a purchase agreement, dated as of June 14, 2010 (the “Purchase Agreement”), U.S. $500,000,000 aggregate principal amount of its 3.625% Senior Notes Due 2015 (the “2015 Notes”) and U.S. $500,000,000 aggregate principal amount of its 5.000% Senior Notes Due 2020 (the “2020 Notes”) (the 2015 Notes and the 2020 Notes are collectively referred to herein as the “Initial Securities”) to the several initial purchasers named in Schedule A to the Purchase Agreement (collectively, the “Initial Purchasers”). The Initial Securities will be issued pursuant to an Indenture, dated as of even date herewith, between the Company and The Bank of New York Mellon Trust Company, N.A., as Trustee (the “Trustee”), as supplemented by the First Supplemental Indenture, dated as of even date herewith, among the Company, the Subsidiary Guarantor(s) party thereto from time to time and the Trustee

RECITALS
Supplemental Agreement • January 2nd, 2001 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
THIRD AMENDED AND RESTATED RENEWED RIGHTS AGREEMENT
Rights Agreement • July 1st, 2003 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts

THIRD AMENDED AND RESTATED RENEWED RIGHTS AGREEMENT Exhibit A—TERMS OF THE JUNIOR PARTICIPATING PREFERRED STOCK EXHIBIT B—FORM OF RIGHT CERTIFICATE TABLE OF CONTENTS

PURCHASE AGREEMENT
Purchase Agreement • November 14th, 1997 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
EXHIBIT 2 STOCK PURCHASE AGREEMENT BY AND BETWEEN
Stock Purchase Agreement • November 8th, 1999 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
PARTICULARS and
Sale Agreement • November 9th, 2001 • Genzyme Corp • Biological products, (no disgnostic substances)
FIRST SCHEDULE PREMISES
Lease Agreement • November 9th, 2001 • Genzyme Corp • Biological products, (no disgnostic substances)
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