AMONG: SGF SANTE INC., a corporation duly incorporated pursuant to the laws of the Province of Quebec, having its head office at 600 de La Gauchetiere Street West, Suite 1700, Montreal, Quebec, H3B 4L8, acting and represented herein by Dupuis Angers,...Subscription Agreement • May 14th, 2003 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMay 14th, 2003 Company Industry
Exhibit 4.8 SHARE PURCHASE AGREEMENT entered into as of July 16, 2003. BETWEEN : MOHAMMED BARKAT, businessman, residing at 146 MacDonald, Kirkland, Quebec, H9J 3Z3 (the "VENDOR") AND : DRAXIS PHARMA INC., a corporation duly incorporated under the laws...Share Purchase Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
DEPRENYL LOGO]License Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledJune 29th, 2001 Company Industry
EXHIBIT 4.14 LOAN AGREEMENT entered into in Montreal as of March 28, 2002. BETWEEN: DRAXIS PHARMA INC., a corporation having an office at 16751 Trans- Canada, Kirkland, Quebec, H9H 4J4 (the "Borrower") AND: Investissement Quebec, a legal person having...Loan Agreement • May 20th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledMay 20th, 2002 Company Industry Jurisdiction
AMONG: DRAXIS HEALTH INC., a corporation incorporated under the laws of Canada, having its head office at 6870 Goreway Drive, Mississauga, Ontario, L4V 1P1, acting and represented herein by Dr. Jim Garner, its Senior Vice President, Finance and Chief...Shareholder Agreement • May 20th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledMay 20th, 2002 Company Industry Jurisdiction
EXHIBIT 3.1 UNDERWRITING AGREEMENT 4,220,466 COMMON SHARES DRAXIS HEALTH INC.Underwriting Agreement • June 17th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledJune 17th, 2002 Company Industry Jurisdiction
ARTICLE 1Subscription Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledJune 29th, 2001 Company Industry Jurisdiction
Second AmendmentMaster Agreement • May 20th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMay 20th, 2002 Company Industry
PERSONAL AND CONFIDENTIAL DELIVERED Dr. Martin Barkin 54 Old Forest Hill Road Toronto, Ontario M5P 2P9 Dear Dr. Barkin: Since January 24, 1992, the date you executed your original employment agreement (the "Original Agreement"), Draxis Health Inc....Employment Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledJune 29th, 2001 Company Industry Jurisdiction
PERSONAL & CONFIDENTIAL Mr. Mark Oleksiw 4265 Pinewood, Pierrefonds, Quebec H9H 2W1 Since June 24th, 2002, the date you executed your original employment agreement (the "Original Agreement"), DRAXIS Health Inc. ("DRAXIS" or the "Corporation") has...Employment Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
DR. MARTIN BARKIN President and CEO Mississauga Location Tel: (905) 677-0898 #236 Fax: (905) 677-5494 Cellular: (416) 726-8870 mbarkin@draxis.com March 26, 2004 PERSONAL & CONFIDENTIAL Ms. Alida Gualtieri 11026 Paris Street Montreal- Nord, Quebec H2H...Employment Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMay 14th, 2004 Company Industry
October 18, 2000 PERSONAL & CONFIDENTIAL DELIVERED Mr. Jack A. Carter 207-606 Shaughnessy Blvd. North York, Ontario M2J 1J9 Dear Mr. Carter: Since August 14, 1998, the date you executed your original employment agreement (the "Original Agreement"),...Employment Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledJune 29th, 2001 Company Industry Jurisdiction
PERSONAL & CONFIDENTIAL Mr. Danny Brazier 316 Lori Avenue Stouffville, Ontario L4A 6C2 Since July 17, 1998, the date you executed your original employment agreement (the "Original Agreement"), and April 15, 1999 the date you executed your revised...Employment Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
Exhibit 4.12 UNDERWRITING AGREEMENT April 2, 2004 DRAXIS HEALTH INC. 6870 Goreway Drive Suite 200 Mississauga, Ontario L4V 1P1 ATTENTION: MARTIN BARKIN, PRESIDENT AND CHIEF EXECUTIVE OFFICER Dear Sirs: Desjardins Securities Inc. and CIBC World Markets...Underwriting Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
Exhibit 4.13 DATED the 22nd day of July, 2003 BETWEEN DRAXIS HEALTH INC. - and - SHIRE BIOCHEM INC. ASSET PURCHASE AGREEMENT Fraser Milner Casgrain LLP 1 First Canadian Place 100 King Street West Toronto, Ontario M5X 1B2 TABLE OF CONTENTSAsset Purchase Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
PERSONAL & CONFIDENTIAL Mr. Chien Huang 121 St. Lawrence Drive Mississauga, ON L5G 4V2 Since June 20th, 2001, the date you executed your original employment agreement (the "Original Agreement"), DRAXIS Health Inc. ("DRAXIS" or the "Corporation") has...Employment Agreement • May 14th, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 14th, 2004 Company Industry Jurisdiction
CREDIT AGREEMENTCredit Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledJune 29th, 2001 Company Industry
DRAXIS LETTERHEAD]Distribution Agreement • June 29th, 2001 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • New York
Contract Type FiledJune 29th, 2001 Company Industry Jurisdiction
EXHIBIT 4.28 SHAREHOLDER RIGHTS PLAN AGREEMENT DATED AS OF APRIL 23, 2002Shareholder Rights Plan Agreement • May 20th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMay 20th, 2002 Company Industry Jurisdiction
Re: Employment AgreementEmployment Agreement • March 31st, 2008 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMarch 31st, 2008 Company IndustryFurther to our recent discussions, we hereby confirm that your employment agreement with DRAXIS Health Inc. dated May 15, 2001 and amended March 26, 2004 (the “Employment Agreement”) is hereby amended as follows:
EXCHANGE AGREEMENTExchange Agreement • October 24th, 1996 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Missouri
Contract Type FiledOctober 24th, 1996 Company Industry Jurisdiction
DRAXIS HEALTH SELECTED BY JOHNSON AND JOHNSON CONSUMER COMPANIES, INC. FOR MAJOR CONTRACT MANUFACTURING RELATIONSHIPSupply Agreement • September 5th, 2007 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledSeptember 5th, 2007 Company IndustryMISSISSAUGA, ONTARIO AND MONTREAL, QUEBEC, September 5, 2007 – DRAXIS Pharma, the contract manufacturing division of DRAXIS Health Inc. (TSX: DAX); (NASDAQ: DRAX), has expanded its existing contract manufacturing relationship with Johnson & Johnson Consumer Companies, Inc. DRAXIS Pharma has entered into a definitive supply agreement to provide commercial manufacturing services for a broad portfolio of multiple non-sterile specialty semi-solid products currently marketed in the United States.
March 28, 2002 Draxis Pharma Inc. 6870 Goreway Drive Mississauga, ON L4V 1P1 Attention: Mr. Jim A.H. Garner Senior Vice President, Finance & CFO Dear Mr. Garner Amendment to Credit Facilities for Draxis Pharma Inc. We refer to the credit agreement...Credit Facilities Amendment • May 20th, 2002 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledMay 20th, 2002 Company Industry Jurisdiction
January 31, 2008 BY PERSONAL DELIVERY Mr. Mark OleksiwEmployment Agreement • July 8th, 2008 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledJuly 8th, 2008 Company Industry
Re: Employment AgreementEmployment Agreement • July 8th, 2008 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledJuly 8th, 2008 Company IndustryFurther to the recent Board of Directors, we hereby confirm that your employment agreement with DRAXIS Health Inc. dated October 17, 2003 and amended on March 26, 2004 and January 31, 2008 (the “Employment Agreement”) is hereby amended as follows effective January 1, 2008:
CONFIDENTIAL COPY DISTRIBUTION AGREEMENTDistribution Agreement • March 31st, 2005 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • California
Contract Type FiledMarch 31st, 2005 Company Industry JurisdictionThis Distribution Agreement (this “Agreement”) is entered into this 12th day of July, 2000, by and between Draximage, Inc., a Canadian corporation (“Draximage”), and Syncor International Corporation, a Delaware corporation (“Syncor”).
FIRST AMENDMENT TO DISTRIBUTION AGREEMENTDistribution Agreement • March 31st, 2005 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMarch 31st, 2005 Company IndustryThis First Amendment to Distribution Agreement is made as of this 6th day of August 2003 by and between Cardinal Health 414, Inc., a Delaware corporation formerly known as Syncor International Corporation (“Cardinal Health”), and Draximage, Inc., a Canadian corporation (“Draximage”), and amends that certain Distribution Agreement, dated July 12, 2000 (the “Agreement”), by and between Cardinal Health and Draximage. Initially capitalized terms used but not defined herein shall have the meanings ascribed thereto in the Agreement.
Re: Employment AgreementEmployment Agreement • July 8th, 2008 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledJuly 8th, 2008 Company IndustryFurther to our recent discussions, we hereby confirm that your employment agreement with DRAXIS Health Inc. dated October 17, 2003 and amended on March 26, 2004 (the “Employment Agreement”) is hereby amended as follows:
Re: Employment AgreementEmployment Agreement • March 31st, 2006 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMarch 31st, 2006 Company IndustryBy this letter we hereby confirm that in accordance with your nomination as Chief Executive Officer of DRAXIS Health Inc. (“DRAXIS”) effective October 4, 2005, your employment agreement with DRAXIS dated April 27, 2004 as amended as on August 25, 2004 (collectively referred to as the “Agreement”) is amended as follows:
MASTER AGREEMENTManufacturing Agreement • March 31st, 2006 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMarch 31st, 2006 Company Industry JurisdictionMANUFACTURING AND SUPPLY MASTER AGREEMENT dated as of January 1, 2005 (“Effective Date”), by PFIZER CANADA INC., a Canadian corporation having its principal office located at 17,300 Trans Canada Highway, Kirkland, Quebec, H9J 2M5 (hereinafter “PFIZER”) and DRAXIS PHARMA, a division of DRAXIS Specialty Pharmaceuticals Inc. (an amalgamation of DRAXIS Pharma Inc. and DRAXIMAGE Inc.), a Canadian corporation having its principal manufacturing facilities at 16751 Trans Canada Highway, Kirkland, Quebec, H9H 4J4 (hereinafter “COMPANY”).
SUPPLY AND DISTRIBUTION AGREEMENTSupply and Distribution Agreement • March 31st, 2005 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Quebec
Contract Type FiledMarch 31st, 2005 Company Industry Jurisdictiona company organized and existing under the laws of the Province of Ontario, having its principal place of business at 16711 Trans-Canada Highway West Kirkland, Quebec H9H 3L1
DRAXIS and Isotope Products Laboratories Sign Distribution AgreementDistribution Agreement • March 23rd, 2004 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMarch 23rd, 2004 Company IndustryMississauga, Ontario, March 22, 2004—DRAXIMAGE Inc., the radiopharmaceutical subsidiary of DRAXIS Health Inc. (TSX: DAX, Nasdaq: DRAX), has concluded a distribution agreement with Isotope Products Laboratories (IPL), a California based producer of radioactive sources for Nuclear Medicine and radiography. DRAXIMAGE will market the full line of IPL medical products in Canada, including calibration references for imaging applications plus calibration sources for PET (Positron Emission Tomography) and SPET (Single Photon Emission Tomography), all well-established modes of diagnostic medical imaging. DRAXIMAGE will also introduce the Perflexion™, IPL's new flexible Cobalt-57 flood source, in Canada during the second quarter of 2004.
Exhibit 4.6 AMENDING AGREEMENT THIS AGREEMENT is made as of March 31, 2003 B E T W E E N: DRAXIS HEALTH INC., a corporation incorporated under the laws of Canada (hereinafter referred to as "Draxis")License, Distribution and Supply Agreement • May 14th, 2003 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Delaware
Contract Type FiledMay 14th, 2003 Company Industry Jurisdiction
MANUFACTURE AND SUPPLY AGREEMENT BETWEEN DRAXIS PHARMA, A division of DRAXIS SPECIALTY PHARMACEUTICALS INC. AND JOHNSON & JOHNSON CONSUMER COMPANIES, INC. AS OF SEPTEMBER 4, 2007Manufacture and Supply Agreement • March 31st, 2008 • Draxis Health Inc /Cn/ • Pharmaceutical preparations
Contract Type FiledMarch 31st, 2008 Company IndustryThis Manufacturing and Supply Agreement (the “Agreement”), is entered into as of September 4, 2007 (the “Effective Date”), by and between Johnson & Johnson Consumer Companies, Inc., a New Jersey corporation (“Buyer”), and DRAXIS Pharma, a division of DRAXIS Specialty Pharmaceuticals Inc., a Canadian corporation (“Manufacturer”). Buyer and Manufacturer are each a “Party” and are collectively, the “Parties”.
SUPPLY AGREEMENT BETWEEN GLAXOSMITHKLINE INC. (A wholly owned subsidiary of GlaxoSmithKline plc) AND DRAXIS PHARMA, INC. DATED AS OF DECEMBER 18, 2001Supply Agreement • March 31st, 2005 • Draxis Health Inc /Cn/ • Pharmaceutical preparations • Ontario
Contract Type FiledMarch 31st, 2005 Company Industry JurisdictionTHIS SUPPLY AGREEMENT (the “Agreement”) is entered in Ontario, Canada on December 18, 2001 (the “Effective Date”) by and between GLAXOSMITHKLINE INC., a corporation organized under the laws of Canada (“GSK”) and DRAXIS PHARMA, INC., a corporation organized under the laws of Canada (“Draxis”). GSK and Draxis are sometimes referred to herein individually as a “Party” and collectively as “Parties.”