EXHIBIT 99.1 SECURITIES PURCHASE AGREEMENT -----------------------------Securities Purchase Agreement • February 3rd, 1999 • U S Bioscience Inc • Pharmaceutical preparations • Delaware
Contract Type FiledFebruary 3rd, 1999 Company Industry Jurisdiction
EXHIBIT 10.3.4 FOURTH AMENDMENT TO LEASE AGREEMENT -----------------------------------Lease Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1998 Company Industry
BACKGROUND ----------Lease • March 20th, 1996 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1996 Company Industry
RECITALSRights Agreement • September 24th, 1999 • U S Bioscience Inc • Pharmaceutical preparations • Delaware
Contract Type FiledSeptember 24th, 1999 Company Industry Jurisdiction
EXHIBIT 10.15 AMENDED AND RESTATED LICENSE AGREEMENTLicense Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations • New York
Contract Type FiledMarch 20th, 1998 Company Industry Jurisdiction
Exhibit 10.11.1 AMENDMENT TO MANUFACTURING AGREEMENT This amendment ("AMENDMENT"), dated April 12, 1995, is by and between U.S. Bioscience, Inc. ("USB"), a corporation organized and existing under the laws of the state of Delaware and Applied...Manufacturing Agreement • March 21st, 1997 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 21st, 1997 Company Industry
EXHIBIT 10.39 U.S. Bioscience, Inc. Executive Severance Agreement with C. Boyd ClarkeExecutive Severance Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations • Pennsylvania
Contract Type FiledMarch 20th, 1998 Company Industry Jurisdiction
ANNEX II TO SUBSCRIPTION AGREEMENT (ADVANTAGE) REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT, dated as of November 30, 1995 (this "Agreement"), is made by and between U.S. BIOSCIENCE, INC., a Delaware corporation (the "Company"),...Registration Rights Agreement • December 28th, 1995 • U S Bioscience Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 28th, 1995 Company Industry Jurisdiction
ANNEX I TO NOTE PURCHASE AGREEMENT (ADVANTAGE) THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. THE SECURITIES HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE SOLD, TRANSFERRED OR...Note Purchase Agreement • December 28th, 1995 • U S Bioscience Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 28th, 1995 Company Industry Jurisdiction
EXHIBIT 10.3.3 THIRD AMENDMENT TO LEASE AGREEMENT ----------------------------------Lease Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1998 Company Industry
BACKGROUND ----------Lease • July 31st, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledJuly 31st, 1998 Company Industry
EXHIBIT 10.25.1 STOCK PURCHASE AGREEMENT ------------------------ THIS STOCK PURCHASE AGREEMENT is made as of the 3rd day of February, 1997, by and between U.S. Bioscience, Inc., a Delaware corporation ("USB"), and ALZA Corporation, a Delaware...Stock Purchase Agreement • February 10th, 1997 • U S Bioscience Inc • Pharmaceutical preparations • Delaware
Contract Type FiledFebruary 10th, 1997 Company Industry Jurisdiction
April 30, 1998 Robert L. Capizzi, M.D. 100 Turnbridge Circle Haverford, PA 19041 Re: Agreement dated as of March 4, 1996, as amended (the "Agreement") Dear Dr Capizzi: The purpose of this letter is to confirm our arrangements to extend your consulting...Consulting Agreement • March 19th, 1999 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 19th, 1999 Company Industry
May 5, 1997Consulting Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1998 Company Industry
RECITALSDistribution and Marketing Collaboration Agreement • February 10th, 1997 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledFebruary 10th, 1997 Company Industry
April 30, 1998 Robert L. Capizzi, M.D. 100 Turnbridge Circle Haverford, PA 19041 Re: AGREEMENT DATED AS OF MARCH 4, 1996, AS AMENDED (THE "AGREEMENT") ----------------------------------------------------------------- Dear Dr Capizzi: The purpose of...Consulting Agreement • May 12th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMay 12th, 1998 Company Industry
AMENDMENTLicense Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1998 Company Industry
AGREEMENT ---------Employment Agreement • March 20th, 1996 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1996 Company Industry
Exhibit 2 NOTE PURCHASE AGREEMENT (ADVANTAGE)Note Purchase Agreement • December 28th, 1995 • U S Bioscience Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 28th, 1995 Company Industry Jurisdiction
AMONGMerger Agreement • September 24th, 1999 • U S Bioscience Inc • Pharmaceutical preparations • Delaware
Contract Type FiledSeptember 24th, 1999 Company Industry Jurisdiction
AGREEMENTConsulting Agreement • March 19th, 1999 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 19th, 1999 Company Industry
Exhibit 1 SUBSCRIPTION AGREEMENT (ADVANTAGE)Subscription Agreement • December 28th, 1995 • U S Bioscience Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 28th, 1995 Company Industry Jurisdiction
EXHIBIT 10.16.1* * The confidential material contained herein has been omitted and has been filed separately with the Commission. AMENDMENT TO DISTRIBUTION AND SUPPLY AGREEMENT ---------------------------------------------- This amendment...Distribution and Supply Agreement • December 19th, 1996 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledDecember 19th, 1996 Company Industry
DATE: March 4, 1997Severance Arrangement • March 21st, 1997 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 21st, 1997 Company Industry
RECITALSStock Option Agreement • September 24th, 1999 • U S Bioscience Inc • Pharmaceutical preparations • Delaware
Contract Type FiledSeptember 24th, 1999 Company Industry Jurisdiction
Exhibit 10.28.1 AGREEMENT ---------Employment Agreement • March 20th, 1998 • U S Bioscience Inc • Pharmaceutical preparations
Contract Type FiledMarch 20th, 1998 Company Industry