Matrix Pharmaceutical Inc/De Sample Contracts

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PURCHASE AND SALE AGREEMENT AND JOINT ESCROW INSTRUCTIONS February 3, 1998 BY AND BETWEEN ALEXANDRIA REAL ESTATE EQUITIES, INC.
Purchase and Sale Agreement • May 11th, 1998 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • California
RECITALS
Termination Agreement • March 31st, 1998 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations
LEASE
Lease Agreement • May 11th, 1998 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • California
RECITALS
License Agreement • November 19th, 1998 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • Delaware
LOGO] IMPERIAL BANK Member FDIC
Credit Agreement • November 12th, 1997 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • California
WITNESSETH:
Non-Statutory Stock Option Agreement • July 28th, 1997 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • California
WITNESSETH
Settlement Agreement • May 11th, 1998 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations
CONFIDENTIALITY AND STANDSTILL AGREEMENT
Confidentiality Agreement • January 14th, 2002 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • Delaware

This Confidentiality and Standstill Agreement between Matrix Pharmaceutical, Inc. ("Matrix") and Chiron ("Chiron") (the "Agreement") is entered into as of this third day of October 2001. Matrix and Chiron are considering whether to explore the possibility of a mutually beneficial transaction (the "Transaction"). In this connection Matrix has requested or may request certain information from Chiron and Chiron has requested or may request certain information from Matrix. This Agreement sets forth certain restrictions to which the parties are agreeing because they are exchanging information with each other. As used in this Agreement, (i) the term "Matrix," and the terms "it" and "its" when used to describe Matrix, shall include Matrix and each Affiliate (as defined in SEC Rule 12b-2) of Matrix and (ii) the term "Chiron," and the terms "it" and "its" when used to describe Chiron, shall include Chiron and each Affiliate of Chiron. The term "person" as used in this Agreement shall be broadly

AGREEMENT AND PLAN OF MERGER Among MATRIX PHARMACEUTICAL, INC., CHIRON CORPORATION, and MANON ACQUISITION CORP. Dated as of January 6, 2002
Merger Agreement • January 14th, 2002 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations • Delaware

AGREEMENT AND PLAN OF MERGER, dated as of January 6, 2002 (this "Agreement"), by and among Chiron Corporation, a Delaware corporation ("Parent"), Manon Acquisition Corp., a Delaware corporation and wholly-owned subsidiary of Parent ("Merger Sub"), and Matrix Pharmaceutical, Inc., a Delaware corporation (the "Company").

Dear Stockholder:
Merger Agreement • January 14th, 2002 • Matrix Pharmaceutical Inc/De • Pharmaceutical preparations
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