OFOperating Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Delaware
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
WITNESSETH:Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research
Contract Type FiledAugust 24th, 2004 Company Industry
CONFIDENTIAL CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. JOINT VENTURE AGREEMENTJoint Venture Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledJune 8th, 2004 Company Industry Jurisdiction
EXHIBIT 4.6 REGISTRATION RIGHTS AGREEMENT This Agreement for Provision of Registration Rights (the "Agreement") is executed as of the 21st day of January, 1998 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company"). W I T N E S S E T...Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
ARTICLE IOffice Lease Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledJune 8th, 2004 Company Industry Jurisdiction
Confidential Amendment to Exclusive License Agreement This letter agreement is being entered into for the purpose of amending that certain Exclusive License Agreement ( the "License Agreement"), executed as of August 3, 1993, between Gopal M. Nair,...Exclusive License Agreement • March 2nd, 2001 • Bionumerik Pharmaceuticals Inc
Contract Type FiledMarch 2nd, 2001 Company
WITNESSETH:Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
AGREEMENT FORBioNumerik Pharmaceuticals, Inc. • March 22nd, 2005 • Services-commercial physical & biological research • Texas
Company FiledMarch 22nd, 2005 Industry Jurisdiction
WITNESSETH:Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
EXHIBIT 4.15 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is executed as of the 8th day of November, 2004 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company"), and Takeda Pharmaceuticals...Registration Rights Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Texas
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
Exhibit A REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is executed as of the 14th day of March, 2000 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company") and Grelan Pharmaceutical Co., Ltd., a...Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
RECITALSIndemnification Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Texas
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
AMONGJoint Venture Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Texas
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
EXHIBIT 9.2 VOTING TRUST AGREEMENT This Voting Trust Agreement (this "Agreement"), dated as of May 30, 2003, is entered into by and between Dasharatha G. Reddy ("Dr. Reddy") and Dhanabalan Murali ("Dr. Murali") (Dr. Reddy and Dr. Murali collectively,...Voting Trust Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research
Contract Type FiledAugust 24th, 2004 Company Industry
EXHIBIT 10.13 COLLABORATION AGREEMENTCollaboration Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research
Contract Type FiledMarch 22nd, 2005 Company Industry
EXHIBIT 4.16 BIONUMERIK PHARMACEUTICALS, INC. CONVERTIBLE PREFERRED STOCK PURCHASE AGREEMENT NOVEMBER 4, 2004 BIONUMERIK PHARMACEUTICALS, INC. CONVERTIBLE PREFERRED STOCK PURCHASE AGREEMENT This Convertible Preferred Stock Purchase Agreement (this...Convertible Preferred Stock Purchase Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • New York
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
Confidential REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is executed as of the 3rd day of October, 2000 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company") and Grelan Pharmaceutical Co.,...Registration Rights Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledJune 8th, 2004 Company Industry Jurisdiction
CONFIDENTIAL VOTING TRUST AGREEMENT This Voting Trust Agreement (this "Agreement"), dated as of May 30, 2003, is entered into by and between Dasharatha G. Reddy ("Dr. Reddy") and Dhanabalan Murali ("Dr. Murali") (Dr. Reddy and Dr. Murali collectively,...Voting Trust Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research
Contract Type FiledJune 8th, 2004 Company Industry
Exhibit 4.8 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is executed as of the 3rd day of October, 2000 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company") and Grelan Pharmaceutical Co., Ltd.,...Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
RECITALSTrials Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Maryland
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
RECITALS:Test Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Washington
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
CONFIDENTIAL CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. STRATEGIC ALLIANCE AGREEMENTStrategic Alliance Agreement • March 2nd, 2001 • Bionumerik Pharmaceuticals Inc
Contract Type FiledMarch 2nd, 2001 Company
CONFIDENTIAL CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. STRATEGIC ALLIANCE AGREEMENTStrategic Alliance Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research
Contract Type FiledJune 8th, 2004 Company Industry
EXHIBIT 10.15 CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. LICENSE AND DEVELOPMENT ALLIANCE AGREEMENT TAKEDA...License and Development Alliance Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • New York
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
EXHIBIT 10.1 CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. STRATEGIC ALLIANCE AGREEMENTStrategic Alliance Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research
Contract Type FiledMarch 22nd, 2005 Company Industry
RECITALSStock Purchase Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
1 EXHIBIT 10.6 CERTAIN INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTION. COLLABORATION AGREEMENTCollaboration Agreement • March 2nd, 2001 • Bionumerik Pharmaceuticals Inc • Texas
Contract Type FiledMarch 2nd, 2001 Company Jurisdiction
EXHIBIT 9.3 VOTING AGREEMENT This Voting Agreement ("Agreement") is executed as of November 8, 2004 between Takeda Pharmaceutical Company Limited, a Japanese corporation located at 4-1-1 Doshomachi, Chuo-ku, Osaka 540-8645, Japan (hereinafter...Voting Agreement • March 22nd, 2005 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Texas
Contract Type FiledMarch 22nd, 2005 Company Industry Jurisdiction
EXHIBIT 4.9 SERIES H REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is executed as of the 2nd day of December, 2003 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company"). W I T N E S S E T H:...Series H Registration Rights Agreement • June 8th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledJune 8th, 2004 Company Industry Jurisdiction
AGREEMENT FORBionumerik Pharmaceuticals Inc • June 8th, 2004 • Services-commercial physical & biological research • Texas
Company FiledJune 8th, 2004 Industry Jurisdiction
AGREEMENT FORBionumerik Pharmaceuticals Inc • August 24th, 2004 • Services-commercial physical & biological research • Texas
Company FiledAugust 24th, 2004 Industry Jurisdiction
EXCLUSIVE LICENSE AGREEMENT GOPAL M. NAIR AND BIONUMERIK PHARMACEUTICALS, INC. FOR MDAM, MEDAM, AND ANALOGSBionumerik Pharmaceuticals Inc • March 2nd, 2001 • Texas
Company FiledMarch 2nd, 2001 Jurisdiction
EXHIBIT 4.5 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the" Agreement") is executed as of the 10th day of July, 1996 by BioNumerik Pharmaceuticals, Inc., a Texas corporation (the "Company") and Grelan Pharmaceutical Co., Ltd., a...Registration Rights Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
RECITALSStock Purchase Agreement • August 24th, 2004 • Bionumerik Pharmaceuticals Inc • Services-commercial physical & biological research • Texas
Contract Type FiledAugust 24th, 2004 Company Industry Jurisdiction
WITNESSETH:Series a Registration Rights Agreement • October 14th, 2004 • BioNumerik Pharmaceuticals, Inc. • Services-commercial physical & biological research • Delaware
Contract Type FiledOctober 14th, 2004 Company Industry Jurisdiction