EXHIBIT 4.1 SUBSCRIPTION AGREEMENT ENCHIRA BIOTECHNOLOGY CORPORATIONSubscription Agreement • September 21st, 2000 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
LICENSE AGREEMENTLicense Agreement • November 14th, 2000 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
EXHIBIT 4.2 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR THE SECURITIES LAWS OF ANY STATE. SUCH SECURITIES MAY NOT BE SOLD OR...Common Stock Purchase Warrant • September 21st, 2000 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Delaware
SUBSCRIPTION AGREEMENT ------------------------------- ENERGY BIOSYSTEMS CORPORATION 7,500,000 SHARES OF COMMON STOCK To: Energy BioSystems Corporation This Subscription Agreement (this "Subscription Agreement" or the "Agreement") is made between...Subscription Agreement • August 16th, 1999 • Energy Biosystems Corp • Services-commercial physical & biological research • Texas
EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT is made this 4th day of December, 1998 by and between Energy BioSystems Corporation, a Delaware corporation (the "Company"), and Peter P. Policastro, Ph.D. ("Employee"). W I T N E S S E T H : WHEREAS, the...Employment Agreement • March 31st, 1999 • Energy Biosystems Corp • Services-commercial physical & biological research • Texas
BETWEENStock Purchase Agreement • March 31st, 1997 • Energy Biosystems Corp • Services-commercial physical & biological research • Delaware
REGISTRATION RIGHTS AGREEMENTRegistration Rights Agreement • May 15th, 1998 • Energy Biosystems Corp • Services-commercial physical & biological research • Delaware
W I T N E S S E T H :Employment Agreement • March 31st, 1998 • Energy Biosystems Corp • Services-commercial physical & biological research • Texas
WITNESSETH:Collaboration Agreement • November 13th, 2000 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
EXHIBIT 4.7 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR THE SECURITIES LAWS OF ANY STATE. SUCH SECURITIES MAY NOT BE SOLD OR...Common Stock Purchase Warrant • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Delaware
EXHIBIT 4.5 THIRD AMENDMENT TO STOCKHOLDER RIGHTS AGREEMENT THIS THIRD AMENDMENT TO STOCKHOLDER RIGHTS AGREEMENT (this "Amendment"), is executed by and between Enchira Biotechnology Corporation (f/k/a Energy BioSystems Corporation), a Delaware...Stockholder Rights Agreement • February 25th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Delaware
WITNESSETHStockholders Rights Agreement • June 23rd, 2000 • Energy Biosystems Corp • Services-commercial physical & biological research
EXHIBIT 10.8 EXTENSION, MODIFICATION AND RATIFICATION OF LEASE This Extension, Modification and Ratification of Lease is made and entered into, effective the 27th day of January, 1994, between The Woodlands Corporation ("Lessor") and Energy BioSystems...Lease Agreement • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research
EXHIBIT 10.7 LEASE AGREEMENT VENTURE TECHNOLOGY CENTER V BUILDING THE WOODLANDS, MONTGOMERY COUNTY, TEXAS STATE OF TEXAS COUNTY OF MONTGOMERY THIS LEASE AGREEMENT (the "Lease") is made and entered into on this the 24th day of May, 1993, between THE...Lease Agreement • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
EXHIBIT 10.36 EXTENSION, MODIFICATION AND RATIFICATION OF LEASE This Extension, Modification and Ratification of Lease ("Extension") is made and entered into, effective the 23rd day of March, 1998, between WOODLANDS OFFICE EQUITIES-'95 LIMITED, a...Lease Agreement • March 31st, 1999 • Energy Biosystems Corp • Services-commercial physical & biological research
ARTICLE ISite License Agreement • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
EXTENSION OF RESEARCH COLLABORATION AGREEMENT The parties to the Research Collaboration Agreement dated July 8, 1993, Energy BioSystems Corporation and Texaco Group, Inc. (by assignment from Texaco, Inc.), hereby agree to extend this Agreement for one...Research Collaboration Agreement • August 13th, 1997 • Energy Biosystems Corp • Services-commercial physical & biological research
October 15, 2002Termination of Employment Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research
This letter (the “Letter”) will reflect our agreement relative to the termination of your employment agreement with Enchira Biotechnology Corporation (the “Company”) and outline a number of practical administrative issues resulting therefrom as well as the potential sale of certain assets of the Company to you.
ASSET TRANSFER AND SUBLICENSE AGREEMENTAsset Transfer and Sublicense Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research
THIS ASSET TRANSFER AND SUBLICENSE AGREEMENT, dated and effective as of September 20, 2002 (the “Effective Date”), is by and between [ ** ] (“[ ** ]”), having its principal place of business at [ ** ], and ENCHIRA BIOTECHNOLOGY CORPORATION, a Delaware corporation (“Enchira”), having its principal place of business at 4200 Research Forest Drive, The Woodlands, TX 77381 (collectively, the “Parties”).
AndStockholder Rights Agreement • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Delaware
EXHIBIT 10.36 THIRD AMENDMENT AND ADDENDUM TO COLLABORATION AGREEMENT This Third Amendment and Addendum (the "Third Amendment") is made and entered into as of the 24th day of August, 1995, by and between Energy BioSystems Corporation, a Delaware...Collaboration Agreement • March 31st, 1997 • Energy Biosystems Corp • Services-commercial physical & biological research
SETTLEMENT AND RELEASE AGREEMENTSettlement and Release Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This Settlement and Release Agreement (the “Settlement and Release Agreement”) is made this 16th day of August, 2002 (the “Effective Date”), by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Paul G. Brown, III (“Brown”).
SECOND AMENDMENT TO EMPLOYMENT AGREEMENTEmployment Agreement • May 15th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This Second Amendment to Employment Agreement (the “Amendment”) is made and entered into by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Paul G. Brown, III (the “Employee”), as of this 2nd day of April, 2002, to be effective as of January 1, 2002.
FIRST AMENDMENT TO EMPLOYMENT AGREEMENTEmployment Agreement • May 15th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This First Amendment to Employment Agreement (the “Amendment”) is made and entered into by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Peter P. Policastro, Ph.D. (the “Employee”), as of this 22nd day of March, 2002, to be effective as of January 1, 2002.
EMPLOYMENT TERMINATION AND SEVERANCE AGREEMENT THIS EMPLOYMENT TERMINATION AND SEVERANCE AGREEMENT (this "Termination Agreement") is entered into as of September 30, 1997, by and between Energy BioSystems Corporation ("EBC"), and John H. Webb, an...Employment Agreement • March 31st, 1998 • Energy Biosystems Corp • Services-commercial physical & biological research • Texas
1. PROTOCOLSponsored Laboratory Study Agreement • April 2nd, 2001 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
FIRST AMENDMENT TO EMPLOYMENT AGREEMENTEmployment Agreement • May 15th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This First Amendment to Employment Agreement (the “Amendment”) is made and entered into by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and David Carpi (the “Employee”), as of this 2nd day of April, 2002, to be effective as of January 1, 2002.
THIRD AMENDMENT TO EMPLOYMENT AGREEMENTEmployment Agreement • May 15th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This Third Amendment to Employment Agreement (the “Amendment”) is made and entered into by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Daniel J. Monticello (the “Employee”), as of this 2nd day of April, 2002, to be effective as of January 1, 2002.
FOURTH AMENDMENT TO EMPLOYMENT AGREEMENTEmployment Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This Fourth Amendment to Employment Agreement (the “Amendment”) is made and entered into by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Daniel J. Monticello (the “Employee”), as of this 15th day of August, 2002 (the “Effective Date”).
SERIES B CONVERTIBLE PREFERRED STOCK EXCHANGE AGREEMENT between ENERGY BIOSYSTEMS CORPORATION and THE EXCHANGING PARTY LISTED ON SCHEDULE IStock Exchange Agreement • March 31st, 1997 • Energy Biosystems Corp • Services-commercial physical & biological research • Delaware
SETTLEMENT AND RELEASE AGREEMENTSettlement & Release Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This Settlement and Release Agreement (the “Settlement and Release Agreement”) is made this 15th day of August, 2002 (the “Effective Date”), by and between Enchira Biotechnology Corporation, a Delaware corporation (the “Company”), and Daniel J. Monticello (“Monticello”).
CONSULTING AGREEMENTConsulting Agreement • November 19th, 2002 • Enchira Biotechnology Corp • Services-commercial physical & biological research • Texas
This CONSULTING AGREEMENT (this “Agreement”) is entered into as of the 16th day of August, 2002 (the “Effective Date”) by and between ENCHIRA BIOTECHNOLOGY CORPORATION, a Delaware corporation (the “Company”), and Paul G. Brown, III (“Consultant” or “Mr. Brown”).
