Hancock John Institutional Series Trust Sample Contracts

Standard Contracts

JOHN HANCOCK INSTITUTIONAL SERIES TRUST 101 Huntington Avenue Boston, MA 02199
Distribution Agreement • January 5th, 1996 • Hancock John Institutional Series Trust
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JOHN HANCOCK INSTITUTIONAL SERIES TRUST 101 Huntington Avenue Boston, MA 02199
Transfer Agency and Service Agreement • January 5th, 1996 • Hancock John Institutional Series Trust
MASTER CUSTODIAN AGREEMENT
Master Custodian Agreement • April 27th, 1999 • Hancock John Institutional Series Trust • Massachusetts
JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Sub-Investment Management Contract Dated May11, 2001 JOHN HANCOCK ADVISERS, INC. 101 Huntington Avenue Boston, Massachusetts 02199 JOHN HANCOCK INSTITUTIONAL SERIES TRUST -...
Sub-Investment Management Contract • October 29th, 2001 • Hancock John Institutional Series Trust • Massachusetts

JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Sub-Investment Management Contract Dated May11, 2001 JOHN HANCOCK ADVISERS, INC. 101 Huntington Avenue Boston, Massachusetts 02199 JOHN HANCOCK INSTITUTIONAL SERIES TRUST - John Hancock International Equity Fund 101 Huntington Avenue Boston, Massachusetts 02199 NICHOLAS-APPLEGATE CAPITAL MANAGEMENT 600 West Broadway San Diego, California 92101 Sub-Investment Management Contract Ladies and Gentlemen: John Hancock Institutional Series Trust (the "Trust") has been organized as a business trust under the laws of The Commonwealth of Massachusetts to engage in the business of an investment company. The Trust's shares of beneficial interest may be classified into series, each series representing the entire undivided interest in a separate portfolio of assets. Series may be established or terminated from time to time by action of the Board of Trustees of the Trust. As of the date hereof, the Trust has eleven series

JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Interim Sub-Investment Management Contract
Interim Sub-Investment Management Contract • April 25th, 2001 • Hancock John Institutional Series Trust • Massachusetts
JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Sub-Investment Management Contract
Sub-Investment Management Contract • June 25th, 2001 • Hancock John Institutional Series Trust • Massachusetts
JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Second Interim Sub-Investment Management Contract
Sub-Investment Management Contract • April 25th, 2001 • Hancock John Institutional Series Trust • Massachusetts
February 3, 2000 John Hancock Advisers, Inc. 101 Huntington Avenue Boston, Massachusetts 02199 Re: John Hancock International Equity Fund ("Fund") Ladies and Gentlemen: The Sub-Investment Management Contract between John Hancock Institutional Series...
Sub-Investment Management Contract • April 26th, 2000 • Hancock John Institutional Series Trust

The Sub-Investment Management Contract between John Hancock Institutional Series (the "Trust") on behalf of the Fund, John Hancock Advisers, Inc. (the "Adviser") and John Hancock Advisers International, Ltd. (the "Sub-Adviser"), dated March 30, 1995, and the fee waiver letter dated January 1, 2000 (together the "Contracts"), currently provide that the Sub-Adviser will act as a limited Co-Sub-Adviser with Indocam International Investment Services.

January 1, 2000 John Hancock Advisers, Inc. 101 Huntington Avenue Boston, Massachusetts 02199 Re: John Hancock International Equity Fund ("Fund") Ladies and Gentlemen: The Sub-Investment Contract between John Hancock Institutional Series (the "Trust")...
Sub-Investment Contract • April 26th, 2000 • Hancock John Institutional Series Trust

The Sub-Investment Contract between John Hancock Institutional Series (the "Trust") on behalf of the Fund, John Hancock Advisers, Inc. (the "Adviser") and John Hancock Advisers International, Ltd. (the "Sub-Adviser"), dated March 30, 1995, currently provides that the Adviser will pay the Sub-Adviser quarterly, for each of the preceding 3 months, in arrears a fee at the annual rate of 70% of the investment advisory fee payable to the Adviser while the Fund's average daily net assets are less than $500 million; and 90% of the investment advisory fee payable to the Adviser while the Fund's average daily net assets are $500 million or more. The Fund shall not be liable to the Sub-Adviser for the Sub-Adviser's compensation.

JOHN HANCOCK INSTITUTIONAL SERIES TRUST SUB-INVESTMENT MANAGEMENT CONTRACT
Sub-Investment Management Contract • October 26th, 2007 • Hancock John Institutional Series Trust • Massachusetts

AGREEMENT made this 14th day of July, 2006, among John Hancock Advisers, LLC, a Delaware limited liability company (the “Adviser”), Independence Investments, LLC a Delaware limited liability company (the “Sub-adviser”) and John Hancock Institutional Series Trust, a business trust under the laws of the Commonwealth of Massachusetts (the “Trust”) on behalf of the John Hancock Independence Diversified Core Equity Fund II (the “Fund”), a series of the Trust. In consideration of the mutual covenants contained herein, the parties agree as follows:

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