BY FACSIMILE AND EXPRESS MAIL CONFIDENTIAL Peter A. Lankau President Endo Pharmaceuticals Inc. Chadds Ford, PA 19317
Exhibit 10.41
November 22, 2004
BY FACSIMILE AND EXPRESS MAIL
CONFIDENTIAL
Xxxxx X. Xxxxxx
President
Endo Pharmaceuticals Inc.
000 Xxxxxxxx Xxxxx
Xxxxxx Xxxx, XX 00000
Re: Amendment 2 to Development, Commercialization and Supply License Agreement
Dear Xxxxx:
Reference is made to the Development, Commercialization and Supply License Agreement between Endo Pharmaceuticals Inc. (“Endo”) and DURECT Corporation (“DURECT”) effective November 8, 2002, as amended effective January 28, 2004 (“Agreement”). Effective on the date written above, Endo and DURECT hereby agree to amend the Agreement as follows:
1. | Amendment to Section 4.6(a). Section 4.6(a) of the Agreement shall be amended to replace each instance of “January 1, 2005” with “January 1, 2006”. |
2. | Amendment to Section 4.6(c). Section 4.6(c) of the Agreement shall be amended to replace each instance of “January 1, 2005” with “January 1, 2006”. |
3. | Amendment to Section 13.3(e). Section 13.3(e) of the Agreement shall be amended to replace “January 1, 2005” with “January 1, 2006” and “January 31, 2005” with “January 31, 2006”. |
Except as set forth above, all other terms of the Agreement shall remain the same. Please sign below to indicate Endo’s agreement to the foregoing.
Very truly yours, |
/s/ Xxxxx X. Xxxxx |
Xxxxx X. Xxxxx |
President and CEO |
AGREED TO BY ENDO: | ||
By: |
/s/ Xxxxx X. Xxxxxx | |
Xxxxx X. Xxxxxx | ||
President |
Date: Nov. 22, 2004