3-MOS MAR-31-1998 JAN-01-1998 MAR-31-1998 439,214 0 521,887 0 0 1,667,970 29,582,947 12,215,553 28,766,338 25,958,709 58,049,800 5,060 0 0 (55,247,231) 28,766,338 825,069 992,914 0 0 8,067,649 0 1,607,437 (8,682,172) 0 (8,682,172) 0 0 0 (8,682,172)...

  

                     5

                       HYBRIDON, INC. AND SUBSIDIARIES
                          (A DEVELOPMENT STAGE COMPANY)

       
                             
                   3-MOS
                               MAR-31-1998
                                  JAN-01-1998
                                    MAR-31-1998
                                              439,214
                                              0
                                       521,887
                                              0
                                               0
                                  1,667,970
                                           29,582,947
                                   12,215,553
                                   28,766,338
                            25,958,709
                                          58,049,800
                                 5,060
                                               0
                                                  0
                                      (55,247,231)
                     28,766,338
                                             825,069
                                    992,914
                                                     0
                                             0
                                  8,067,649
                                          0
                                1,607,437
                                  (8,682,172)
                                              0
                              (8,682,172)
                                            0
                                           0
                                                 0
                                     (8,682,172)
                                         (1.72)
                                         (1.72)