PERLEGEN SCIENCES, INC. AMENDMENT NO. 2 TO SECOND AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT

Exhibit 10.7

PERLEGEN SCIENCES, INC.

AMENDMENT NO. 2 TO

SECOND AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT

     THIS AMENDMENT NO. 2 to the Second Amended and Restated Stockholders’ Agreement is made as of March 1, 2006 (the “Effective Date”), by and among Perlegen Sciences, Inc. a Delaware corporation (the “Company”), the holders of the Company’s Common Stock and Series A Preferred Stock (each an “Investor” and collectively the “Investors”), and the holders of the Company’s Series B Preferred Stock, Series C Preferred Stock, Series D Preferred Stock and Series D-1 Preferred Stock (each a “Prior Purchaser” and collectively the “Prior Purchasers”).

     WHEREAS, the Company is increasing the number of shares in its 2002 Equity Incentive Plan.

     WHEREAS, the Company, the Investors and the Prior Purchasers are parties to that certain Second Amended and Restated Stockholders’ Agreement, dated as of February 1, 2005 and Amendment No. 1 to the Stockholders’ Agreement dated December 22, 2005 (the “Stockholders’ Agreement”);

     WHEREAS, the parties to the Stockholders’ Agreement desire to amend the Stockholders’ Agreement pursuant to Section 15 of the Stockholders’ Agreement to revise Section 2.4(c) to increase the number of shares that the Company may issue without being subject to preemptive rights.

     NOW, THEREFORE, in consideration of the mutual covenants contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows:

     1. The Company, the Investors holding a majority of the Common Stock and Series A Preferred Stock (each as defined in the Stockholders’ Agreement), the Prior Purchasers holding a majority of the Series B Preferred Stock, Series C Preferred Stock, Series D Preferred Stock and Series D-1 Preferred Stock (each as defined in the Stockholders’ Agreement) hereby amend the Stockholders’ Agreement to increase the number of shares the Company may issue without being subject to preemptive rights.

     2. Section 2.4(c) of the Stockholders’ Agreement shall be amended in its entirety as set forth below:

     “The provisions of this Section 2.4 shall not apply to the following issuances of securities or Rights: (i) the issuance of Common Stock upon the conversion of Series A Stock, Series B Stock, Series C Stock, Series D Stock or Series D-1 Stock, (ii) the issuance of up to 41,443,702 shares of Common Stock (subject to adjustment for stock splits, reverse stock splits, subdivisions, stock dividends, combinations, reclassifications, recapitalizations and similar events) pursuant to restricted stock sold to, or the exercise of stock options issued to, employees, consultants, officers or directors of the Company under a stock option plan or restricted stock issuance plan approved by a majority of the board of directors of the Company, (iii) the issuance of Common Stock as direct consideration for the acquisition of

another business entity or business segment of any such entity by the Company by merger, purchase of substantially all of the assets or other reorganization whereby the Company will own substantially all the assets or more than fifty percent (50%) of the voting power of such business entity or business segment of any such entity if such issuance is approved by a majority of the board of directors of the Company, (iv) the issuance of any shares of Common Stock in connection with a stock split or dividend of the Company (other than a Deemed Liquidation Event as defined in the Certificate), (v) the issuance of Common Stock in connection with a Qualified IPO, (vi) the issuance of Common Stock or Preferred Stock in connection with a lease financing or other asset-based financing, whether issued to a lessor, guarantor or other person (a “Lease Financing”), provided that such Lease Financing is approved by a majority of the board of directors of the Company; and provided further that any such Lease Financing which in aggregate amount exceeds $10,000,000 is approved by a majority of the board of directors including the director designated by the holders of the Series C Stock and the director designated by the holders of the Series D Stock, (vii) the issuance of Common Stock or Preferred Stock in connection with a corporate partnering, alliance or similar strategic transaction approved by a majority of the board of directors of the Company, or (viii) the issuance or deemed issuance of Common Stock or Preferred Stock upon exercise or conversion of any options or warrants, or upon the conversion of convertible securities outstanding as of the date of the first issuance of the Series D-1 Stock.”

     3. The Stockholders’ Agreement as modified herein shall remain in full force and effect as so modified.

[REMAINDER OF THIS PAGE IS INTENTIONALLY LEFT BLANK]

     The Parties have executed this Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement as of the Effective Date.

		PERLEGEN SCIENCES, INC.
		By:		/s/ Xxxx X. Xxxxxx
		Name: Xxxx X. Xxxxxx
		Title: President and Chief Executive Officer
		Address:
		Perlegen Sciences, Inc.
		0000 Xxxxxxxx Xxxxx
		Xxxxxxxx Xxxx, Xxxxxxxxxx 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		MAVERICK FUND LDC
		By:		/s/ Xxxx X. XxXxxxxxxx
		Name:		Xxxx X. XxXxxxxxxx
		Title:		Limited Partner & General Counsel
		Address:
		Maverick Capital
		000 Xxxxxxxx Xxxxx, 00xx Xxxxx
		Xxxxxx, XX 00000
		Attn: Xxxx XxXxxxxxxx, General Counsel

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		MAVERICK FUND USA, LTD.
		By:		/s/ Xxxx X. XxXxxxxxxx
		Name:		Xxxx X. XxXxxxxxxx
		Title:		Limited Partner & General Counsel
		Address: Maverick Capital
		000 Xxxxxxxx Xxxxx, 00xx Xxxxx
		Xxxxxx, XX 00000
		Attn: Xxxx XxXxxxxxxx, General Counsel

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		MAVERICK FUND II, LTD.
		By:		/s/ Xxxx X. XxXxxxxxxx
		Name:		Xxxx X. XxXxxxxxxx
		Title:		Limited Partner & General Counsel
		Address Maverick Capital
		000 Xxxxxxxx Xxxxx, 00xx Xxxxx
		Xxxxxx, XX 00000
		Attn: Xxxx XxXxxxxxxx, General Counsel

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		UNILEVER TECHNOLOGY VENTURES FUND B.V.
		By:
		Name: Xxxx Xxxxxx
		Title: Managing Director
		By:		/s/ Xxxx Xxxxxxx
		Name: Xxxx Xxxxxxx
		Title: Managing Director
		Address:
		000 Xxxxxxxxxx Xxxxxx, Xxxxx 000
		Xxx Xxxxxxxxx, XX 00000
		Attention:				Xxxx Xxxxxx
						Xxxx Xxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CMEA VENTURES LIFE SCIENCES 2000, L.P.
		By:		/s/ Xxx Xxxxxx
		Name: Xxx Xxxxxx
		Title: General Partner
		Address:
		CMEA Ventures Life Sciences 2000 Limited Partnership
		Xxx Xxxxxxxxxxx Xxxxxx, Xxxxx 0000
		Xxx Xxxxxxxxx, XX 00000-0000
		Attn: Xxx Xxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CMEA VENTURES LIFE SCIENCES 2000, CIVIL LAW PARTNERSHIP
		By:		/s/ Xxx Xxxxxx
		Name: Xxx Xxxxxx
		Title: General Partner
		Address:
		CMEA Ventures Life Sciences 2000 Civil Law Partnership
		Xxx Xxxxxxxxxxx Xxxxxx, Xxxxx 0000
		Xxx Xxxxxxxxx, XX 00000-0000
		Attn: Xxx Xxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		BSI SA.
		By:		/s/ Xxxxxx Xxxxxxx
		Name:		Xxxxxx Xxxxxxx
		Title:		Assistant Vice President
		By:		/s/ Xxxxxxxx Xxxxxx
		Name:		Xxxxxxxx Xxxxxx
		Title:		Vice President
		Address:
		BSI SA
		Xxxxxx Xxxxxxx
		Assistant Vice President
		Securities Administration
		Xxx Xxxxxxx 0
		0000 Xxxxxx
		Xxxxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		BSI — NEW BIOMEDICAL FRONTIER (SICAV)
		By:		/s/ Xxxxx XxXxxxxxx
		Name:		Xxxxx XxXxxxxxx
		Title:		Manager
		Address: BSI-New BioMedical Frontier (SICAV)
		Xxx Xxxx 00
		0000 Xxxxxx
		Xxxxxxxxxxx
		Attn: Xxxxxxxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		ZAFFARONI REVOCABLE TRUST 1/24/86
		By:		/s/ Xxxxxxxxx Xxxxxxxxx
		Name:		Xxxxxxxxx Xxxxxxxxx
		Title:		Trustee
		Address:
		Xxxxxxx X. Xxxxxxxx
		c/o Technofyn Associates, LLC
		0000 Xxxxxxx Xxxxxx, Xxxxx 000
		Xxxx Xxxx, XX 00000-0000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CSK VENTURE CAPITAL CO., LTD. as Investment Manager for Hitachi CSK Internet Business Fund
		By:		/s/ Xxxxxxxx Xxxxxxxx
		Name:		Xxxxxxxx Xxxxxxxx
		Title:		President
		Address:
		5th Floor, Reviera Xxxxxx Xxxxxx Xxxx.
		0-0-0 Xxxxx-Xxxxxx, Xxxxxx-xx
		Xxxxx 000-0000
		Xxxxx
		Attn: Xxxxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CSK VENTURE CAPITAL CO., LTD. as Investment Manager CSK-4 Investment Fund
		By:		/s/ Xxxxxxxx Xxxxxxxx
		Name:		Xxxxxxxx Xxxxxxxx
		Title:		President
		Address:
		5th Floor, Reviera Xxxxxx Xxxxxx Xxxx.
		0-0-0 Xxxxx-Xxxxxx, Xxxxxx-xx
		Xxxxx 000-0000
		Xxxxx
		Attn: Xxxxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxx X. Xx Xxxxxxx

XXXXX X. XX XXXXXXX

Address:

0000 Xxxx Xxxxx Xxxx

Xxxxxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		THE 1989 LEECH LIVING TRUST
		By:		/s/ Xxx X. Xxxxx
		Name: Xxx X. Xxxxx
		Title: Trustee
		Address: The 1989 Leech Living Trust
		0000 Xxxxxx Xxxx Xxx
		Xxxxxxx Xxxx, XX 00000
		Attn: Xxx Xxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxxxx Xxxxx

XXXXXXX XXXXX

Address: Xxxxxxx Xxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxxxx X. Xxxxxxxx

XXXXXXX X. XXXXXXXX

Address: Xxxxxxx X. Xxxxxxxx

000 Xxxxxxxxx Xxxxx

Xxx Xxxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxxxxxx X. Xxxxxxxxx

XXXXXXXXX X. XXXXXXXXX

Address:

Xxxxxxx X. Xxxxxxxx

c/o Technofyn Associates, LLC

0000 Xxxxxxx Xxxxxx, Xxxxx 000

Xxxx Xxxx, XX 00000-0000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

ALEXANDER XXXXX XXXXXXXXX 12/29/88 TRUST

By:      /s/ Xxxxxxx Xxxxx     Xxxxx Xxxxx

Name:   Xxxxxxx Xxxxx     Xxxxx Xxxxx

Title:     Trustee               Trustee

Address:

Xxxxxxxxx X. Xxxxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

XXXXXXX XXXX XXXXXXXXX 12/29/88 TRUST

By:     /s/ Xxxxxxx Xxxxx     Xxxxx Xxxxx

Name:     Xxxxxxx Xxxxx     Xxxxx Xxxxx

Title:     Trustee                Trustee

Address:

Xxxxxxxxx X. Xxxxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxx Xxxxxxxxx

XXXXX XXXXXXXXX

Address:

Xxxxxxxxx X. Xxxxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxx Xxxxxxxxx

XXXX XXXXXXXXX

Address:

Xxxxxxxxx X. Xxxxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxx Xxxxxxxx

XXXXX XXXXXXXX

Address:

Xxxxx Xxxxxxxx

c/o Technofyn Associates L.L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxx X. Xxxxxxx

XXXXX X. XXXXXXX

Address: Xxxxx Xxxxxxx

c/o Technofyn Associates L.C.

0000 Xxxxxxx Xxxxxx

Xxxxx 000

Xxxx Xxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxx Xxxxxxx Xxxxx

XXXXX XXXXXXX XXXXX

Address:

Xxxxx Xxxxxxx Xxxxx

000 Xxxxxxx Xxxxxx

Xxxxxxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

AFFYMETRIX, INC.

By:      /s/ Xxxx Xxxxxxxxx

Name: Xxxx Xxxxxxxxx

Title:  CFO

Address:

Affymetrix, Inc.

0000 Xxxxxxx Xxxxxxxxxx

Xxxxx Xxxxx, XX 00000

Attn: Xxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

LOMBARD ODIER DARIER XXXXXXX & CIE

By:     proxy /s/ Xxxxxxxxx Xxxxx

Name: Xxxxxxxxx Xxxxx

Title:  Senior Vice President

By:     proxy /s/ Xxxx Xxxxxxx

Name: Xxxx Xxxxxxx

Title: Vice President

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

SCHWEIZERHALL HOLDING AG

SCHWEIZERHALI MANAGEMENT

By:    /s/ L.V. Bidder

Name: L.V. Bidder

Title: CEO

Address:

c/o Xx. Xxxx von Bidder

Xxxxxxxxxxxxxxxx 00

0000 Xxxxxx

Xxxxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

ZAFFARONI FAMILY PARTNERSHIP, LP

By:     /s/ Xxxxxxxxx Xxxxxxxxx

Name: Xxxxxxxxx Xxxxxxxxx

Title:  General & Limited Partner

Address:

Xxxxxxx X. Xxxxxxxx

c/o Technofyn Associates, LLC

0000 Xxxxxxx Xxxxxx, Xxxxx 000

Xxxx Xxxx, XX 00000-0000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

BROOKSIDE CAPITAL PARTNERS FUND, L.P.

By:     /s/ Xxxx XxXxxxxxx

Name: Xxxx XxXxxxxxx

Title: Managing Director

Address:

Brookside Capital Partners Fund, L.P.

000 Xxxxxxxxxx Xxxxxx, 00^xx Xxxxx

Xxxxxx, XX 00000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CALIFORNIA EMERGING VENTURES, LLC
		By: GSA Partners, LLC, its Manager
		By: Grove Street Advisors, LLC, its Manager
		By:		/s/ Xxx St. German
		Name: Xxx St. German
		Title: Member & CFO
		Address:
		Grove Street Advisors
		00 Xxxxxxx Xxxxxx, Xxxxx 000
		Xxxxxxxxx, XX 000000
		Attention: Xxx St. German

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CSK FINANCE CO., LTD.
		By:		/s/ Syoji Wakita
		Name:		Syoji Wakita
		Title:		President
		Address:
		5th Floor, Reviera Xxxxxx Xxxxxx Xxxx.
		0-0-0 Xxxxx-Xxxxxx, Xxxxxx-xx
		Xxxxx 000-0000
		Xxxxx
		Attn: Xxxxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		CSK VENTURE CAPITAL CO., LTD.,
		As Investment Manager for CSK-VC Life
		Science Investment Fund
		By:		/s/ Xxxxxxxx Xxxxxxxx
		Name:		Xxxxxxxx Xxxxxxxx
		Title:		President
		Address:
		5th Floor, Reviera Xxxxxx Xxxxxx Xxxx.
		0-0-0 Xxxxx-Xxxxxx, Xxxxxx-xx
		Xxxxx 000-0000
		Xxxxx
		Attn: Xxxxxx Xxxxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		MAG & CO. FBO FIDELITY MT. XXXXXX
		STREET TRUST: FIDELITY GROWTH
		COMPANY FUND
		By:		/s/ Xx Xxxxxx
		Name:		Xx Xxxxxx
		Title:		Director – Investment Proxy Research Fidelity Management & Research
		Address:
		00 Xxxxxxxxxx Xxxxxx
		Xxxxxx, XX 00000
		Attention: Xxxxxxxx Xxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		SURINVEX INTERNATIONAL
		CORPORATION (FOREIGN CORP.)
		By:		/s/ Xxxx X. Xxxxxxxx
		Name:		Xxxx X. Xxxxxxxx
		Title:		Treasurer

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

/s/ Xxxxxxxxx Xxxxxxx

XXXXXXXXX XXXXXXX

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		XXXXXXXXX XXXXXXXXX, TRUSTEE OF
		ZAFFARONI RETIREMENT TRUST FBO
		XXXXXXX X. XXXXXXXX, U/A/D 1/1/02
		By:		/s/ Xxxxxxxxx Xxxxxxxxx
		Name:		Xxxxxxxxx Xxxxxxxxx
		Title:		Trustee
		Address:
		Xxxxxxx X. Xxxxxxxx
		c/o Technofyn Associates, LLC
		0000 Xxxxxxx Xxxxxx, Xxxxx 000
		Xxxx Xxxx, XX 00000-0000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		XXXXXXXXX XXXXXXXXX, TRUSTEE OF
		ZAFFARONI RETIREMENT TRUST FBO
		M. XXXXXXX XXXXX, U/A/D 1/1/02
		By:		/s/ Xxxxxxxxx Xxxxxxxxx
		Name:		Xxxxxxxxx Xxxxxxxxx
		Title:		Trustee
		Address:
		Xxxxxxx X. Xxxxxxxx
		c/o Technofyn Associates, LLC
		0000 Xxxxxxx Xxxxxx, Xxxxx 000
		Xxxx Xxxx, XX 00000-0000

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		ALSTERTOR PRIVATE LIFE GMBH & CO. KG
		By:		/s/ Xxxxx Xxxxxx          Xxxxxx Xxxxxxxxx
		Name:		Xxxxx Xxxxxx          Xxxxxx Xxxxxxxxx
		Title:		Managing Partners

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		MPM BIOEQUITIES MASTER FUND, LP
		By: MPM BioEquities GP, LP, its General Partner
		By: MPM BioEquities GP, LLC its General Partner
		By:		/s/ Xxxx xxx Xxxxxx
		Name:		Xxxx xxx Xxxxxx
		Title:		Portfolio Manager
		Address:
		MPM Capital, LP
		000 Xxxxxxx Xxxx. #000
		Xxxxx Xxx Xxxxxxxxx, XX 00000
		Attention: Xxxx X. Xxx Xxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement

		PRIVATE LIFE BIOMED AG
		By:		/s/ Xxxxx X. Xxxxxxx          X. Xxxxxxxxx
		Name:		Xxxxx X. Xxxxxxx         X. Xxxxxxxxx
		Title:		Managing Directors
		Address:
		Xxxxx Xxxxxxx
		M.M. Warburrg & CO Schiffahrtstreuhand
		Gesellschaft mit beschränkter Haftung
		Xxxxxxxxxxxxxxx 00-00
		X00000 Xxxxxxx, Xxxxxxx

Signature Page to Perlegen Sciences, Inc.
Amendment No. 2 to the Second Amended and Restated Stockholders’ Agreement