Exhibit 10.4.2
[Merck & Co., Inc. Letterhead]
October 24, 1996
Xx. Xxxxxx Xxxxxxxx
Regeneron Pharmaceutical, Inc.
000 Xxx Xxx Xxxx Xxxxx xxxx
Xxxxxxxxx, XX 00000
Dear Xx. Xxxxxxxx:
This shall serve as a memorandum of our agreement to amend Schedule A of the
Manufacturing Agreement between Merck & Co., Inc. ("Merck") and Regeneron
Pharmaceuticals, Inc. (Regeneron") dated September 18, 1995, so as to permit
Merck to use Room [***], as depicted on the diagram annexed to Schedule A of the
Manufacturing Agreement, in conjunction with Regeneron, for [***] purposes
in support of the manufacture of Product pursuant to said agreement. Room [***]
is indicated in red outline on the diagram attached hereto. Regeneron shall
designate said area as a "[***] area" on the diagram attached to Schedule A of
the Agreement.
In consideration for the [***] use of Room [***] for the term of the Agreement,
Merck, within 60 days of the execution of this letter agreement by Xxxxxxxxx ,
shall remit to Regeneron a one-time payment of [***].
If the foregoing is agreeable, would you please so indicate by signing, dating
and returning to us the enclosed copy of this letter.
Very truly yours,
Merck & Co., Inc.
/s/Xxxx X. Xxxxxx
-------------------------------
Xxxx X. Xxxxxx
Date: 11/25/96
The foregoing is agreed to:
Regeneron Pharmaceuticals, Inc.
/s/Xxxxxx Xxxxxxxx
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Xxxxxx Xxxxxxxx
Date: 11/06/96
