GENTIUM S.P.A. AMENDMENT NO. 1 TO AMENDED AND RESTATED NONSTATUTORY STOCK OPTION PLAN AND AGREEMENT
Exhibit
4.2.2
AMENDMENT
NO. 1 TO
AMENDED
AND RESTATED NONSTATUTORY STOCK OPTION PLAN AND
AGREEMENT
THIS
AMENDMENT NO. 1
to the
Amended and Restated Nonstatutory Stock Option Plan and Agreement (the “Plan”)
of Gentium S.p.A. (the “Company”) is made as of March 26, 2007. All capitalized
terms not defined herein are set forth in the Plan.
WHEREAS,
the
Company wishes to amend the Plan to extend the term of the Plan and the
mandatory subscription date for ordinary shares available under such
Plan;
NOW
THEREFORE,
1. Section
25 of the Plan is hereby amended and restated in its entirety to
read:
25. Effective
Date and Duration of the NSO Plan and Agreement.
The NSO
Plan and Agreement shall be effective as of September 30, 2004. The Board may
suspend or terminate the NSO Plan and Agreement at any time. Unless sooner
terminated, the NSO Plan and Agreement shall terminate at midnight on September
30, 2014.
2. The
Plan
as modified herein shall remain in full force and effect as so
modified.
[Remainder
of page intentionally blank]
To
record
the adoption of this Amendment No. 1 to the Plan by the Board, the Company
has
caused its duly authorized officer to execute this Amendment No. 1 to the Plan
on behalf of the Company.
GENTIUM S.p.A. | ||
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By: | /s/ Xxxxx Xxxx Xxxxx, M.D. | |
Xxxxx Xxxx Xxxxx, M.D. |
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Title: | President and Chief Executive Officer |