Common Contracts

3 similar null contracts by Vertex Pharmaceuticals Inc / Ma

John J. Alam, M.D. 11 Channing Street Cambridge, MA 02138 Re: Second Amendment to Change of Control Agreement Dear John:
Vertex Pharmaceuticals Inc / Ma • February 11th, 2008 • Pharmaceutical preparations

The Change of Control Agreement dated as of March 7, 2003 between you and Vertex Pharmaceuticals Incorporated, as amended effective November 8, 2004 (the "Agreement") hereby is amended, effective February 11, 2008, as follows:

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Richard C. ("Bink") Garrison 337 Marlborough Street, Apt. 3 Boston, MA 02115 Re: Second Amendment to Change of Control Agreement Dear Bink:
Vertex Pharmaceuticals Inc / Ma • February 11th, 2008 • Pharmaceutical preparations

The Change of Control Agreement dated as of December 12, 2005 between you and Vertex Pharmaceuticals Incorporated, as amended to date, (the "Agreement") hereby is amended, effective on that date hereof, as follows:

Lisa Kelly-Croswell 40 Wyman Road Lexington, MA 02420 Re: Amendment to Change of Control Agreement Dear Lisa:
Vertex Pharmaceuticals Inc / Ma • February 11th, 2008 • Pharmaceutical preparations

The Change of Control Agreement dated as of July 12, 2007 between you and Vertex Pharmaceuticals Incorporated (the "Agreement") hereby is amended, effective on the date hereof, as follows:

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