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Clinical Study Agreement • September 14th, 2020

CLINICAL STUDY AGREEMENT SMLOUVA O KLINICKÉ STUDII This Clinical Study Agreement (“Agreement”) is made and entered into as of 20-Dec-2016 (“Effective Date”) by and between, Ústav Hematologie a krevní transfuze located at U Nemocnice 2094/1, 128 20 Praha 2, Czech Republic (“Study Site”), located at U Nemocnice 2094/1, 128 20 Praha 2, Czech Republic (“Principal Investigator”), and Daiichi Sankyo, Inc., located at 399 Thornall Street, Edison, New Jersey 08837, USA (“DSI”). Study Site, Principal Investigator and DSI are each referred to as a “Party” and collectively as the “Parties.” Tato smlouva o klinické studii (dále jen„smlouva”) se uzavírá ke dni 20.12.2016 (dále jen „datum účinnosti”) mezi Ústav Hematologie a krevní transfuze na adrese U Nemocnice 2094/1, 128 20 Praha 2, Česká republika (dále jen „studijní pracoviště”), na adrese U Nemocnice 2094/1, 128 20 Praha 2, Czech Republic (dále jen „hlavní zkoušející”), a společností Daiichi Sankyo, Inc., se sídlem na adrese 399 Thornall

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