ContractClinical Study Agreement • June 8th, 2022
Contract Type FiledJune 8th, 2022AMENDMENT NO. 2 TO CLINICAL STUDY AGREEMENT This Amendment No. 2 is made to the Clinical Study Agreement (“Agreement”) entered into19 March 2019, by and between, Fakultní nemocnice v Motole, located at V Úvalu 84, 150 06 Praha 5, Czech Republic, Identification number: 00064203, Tax identification number: CZ00064203, represented by by delegation (“Study Site”), and Daiichi Sankyo, Inc., located at 211 Mt. Airy Road, Basking Ridge, New Jersey 07920, United States (“DSI”) and IQVIA RDS Czech Republic s.r.o., having a place of business at Pernerova 691/42, 186 00 Praha 8 - Karlín, Czech Republic, Identification number: 247 68 651, Tax identification number: CZ247 68 651, (“CRO”). Study Site and DSI are each referred to as a “Party” and collectively as the “Parties” and is effective as of its publication in the Register of Agreements, but the parties agree to be bound by the rights and obligations arising from this Amendment from 01 January 2021 (“Effective Date”) WITNESSETH: WHEREAS, CRO,