0000875320-13-000009 Sample Contracts

AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • March 1st, 2013 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This Second Amended and Restated Employment Agreement (this “Agreement”) amends and restates, effective as of the 15th day of November, 2012, that certain Amended and Restated Employment Agreement made and entered into as of the 5th day of February, 2010 (the “Original Agreement”) by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the “Company”), and Peter Mueller (the “Executive”).

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November 15, 2012
Change of Control Agreement • March 1st, 2013 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
SEPARATION AGREEMENT & GENERAL RELEASE
Separation Agreement • March 1st, 2013 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

THIS SEPARATION AGREEMENT & GENERAL RELEASE (“Agreement”) is made and entered into by and between DAVID T. “TY” HOWTON (“Employee”) and VERTEX PHARMACEUTICALS INCORPORATED (the “Company”) as of the Effective Date (as such term is defined in Section 12 below).

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