1 EXHIBIT 4.4 SECURITY AGREEMENT THIS SECURITY AGREEMENT is entered into as of the 19th day of August, 1997 by and between Medical Science Systems, Inc., a Texas corporation (the "Borrower") and (the "Secured Party"). 1. Creation of Security Interest....Security Agreement • October 8th, 1997 • Medical Science Systems Inc • California
1 EXHIBIT 4.2 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 (THE "ACT") OR ANY STATE SECURITIES LAWS AND MAY NOT BE OFFERED, SOLD, TRANSFERRED, PLEDGED OR HYPOTHECATED...Medical Science Systems Inc • October 8th, 1997 • Connecticut
OFFICE LEASE ONE INTERNATIONAL CENTREOffice Lease • October 8th, 1997 • Medical Science Systems Inc • Texas
1 EXHIBIT 1.1 MEDICAL SCIENCE SYSTEMS, INC. 1,500,000 SHARES OF COMMON STOCK UNDERWRITING AGREEMENTMedical Science Systems Inc • October 8th, 1997 • Connecticut
LEASEMedical Science Systems Inc • October 8th, 1997
EXHIBIT 10.7 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT ("Agreement"), by and between Medical Science Systems, Inc., a Texas Corporation (the "Corporation"), and Paul J. White ("Employee"), is effective this 1st day of January, 1996 ("Effective...Employment Agreement • October 8th, 1997 • Medical Science Systems Inc
LOGO] BANK OF AMERICA =============================================================================== TO: Bank of America National Trust and Savings Association BUSINESS LOAN AGREEMENT-FIXED RATE Unit No. 1737 SECURED BY PERSONAL PROPERTY...Agreement • October 8th, 1997 • Medical Science Systems Inc • California
1 EXHIBIT 10.8 AMENDMENT TO EMPLOYMENT AGREEMENT THIS AMENDMENT TO EMPLOYMENT AGREEMENT (the "Amendment"), by and between Medical Science Systems, Inc., a Texas corporation (the "Corporation"), and Paul J. White ("Employee"), is effective this 1st day...Employment Agreement • October 8th, 1997 • Medical Science Systems Inc
PARTICIPANT: _________________ SOCIAL SECURITY NUMBER: _________________ ADDRESS: _________________ _________________ TOTAL OPTION SHARES: _________________ EXERCISE PRICE PER SHARE: _________________ DATE OF GRANT: _________________ FIRST VESTING...Form of Stock Option Agreement • October 8th, 1997 • Medical Science Systems Inc • California
1 EXHIBIT 4.7 [BANK OF AMERICA LOGO] =============================================================================== [ ] Business Line [X] Business Loan Agreement Secured TO: Bank of America National Trust and Savings Association Business Lending...Agreement • October 8th, 1997 • Medical Science Systems Inc • California
1 EXHIBIT 10.13 SERVICE AGREEMENT This AGREEMENT is entered into between MEDICAL SCIENCE SYSTEMS, 4400 MACARTHUR BLVD., STE. 980, NEWPORT BEACH, CA 92660 (hereinafter referred to as "COMPANY"), and BAYLOR COLLEGE OF MEDICINE, DEPARTMENT OF MOLECULAR...Agreement • October 8th, 1997 • Medical Science Systems Inc
1 EXHIBIT 10.9 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT ("AGREEMENT"), by and between Medical Science Systems, Inc., a Texas Corporation (the "CORPORATION"), and Kenneth S. Kornman ("EMPLOYEE"), is effective this 1st day of January, 1996...Employment Agreement • October 8th, 1997 • Medical Science Systems Inc
RECITALSProject Agreement • October 8th, 1997 • Medical Science Systems Inc • California
1 EXHIBIT 10.10 AMENDMENT TO EMPLOYMENT AGREEMENT THIS AMENDMENT TO EMPLOYMENT AGREEMENT (the "Amendment"), by and between Medical Science Systems, Inc., a Texas corporation (the "Corporation"), and Dr. Kenneth S. Kornman ("Employee"), is effective...Employment Agreement • October 8th, 1997 • Medical Science Systems Inc
1 EXHIBIT 1.2 MEDICAL SCIENCE SYSTEMS, INC. 1,500,000 SHARES OF COMMON STOCK AGREEMENT AMONG UNDERWRITERSMedical Science Systems Inc • October 8th, 1997
RECITALSMaster Agreement • October 8th, 1997 • Medical Science Systems Inc • California
EXHIBIT 10.20 MEDICAL SCIENCE SYSTEMS, INC. 1996 EQUITY INCENTIVE PLAN STOCK OPTION EXERCISE AGREEMENT This Exercise Agreement is made and entered into as of ________, 199_ (the "Effective Date") by and between Medical Science Systems, Inc., a Texas...Stock Pledge Agreement • October 8th, 1997 • Medical Science Systems Inc • California
EXHIBIT B A REGISTRATION STATEMENT RELATING TO THESE SECURITIES HAS BEEN FILED WITH THE SECURITIES AND EXCHANGE COMMISSION BUT HAS NOT YET BECOME EFFECTIVE. NO OFFER TO BUY THE SECURITIES CAN BE ACCEPTED AND NO PART OF THE PURCHASE PRICE CAN BE...Medical Science Systems Inc • October 8th, 1997
MEDICAL SCIENCE SYSTEMS RESEARCH SUPPORT AGREEMENT AND AMENDMENTS TO VARIOUS EXISTING PROJECT AGREEMENTSMedical Science Systems Inc • October 8th, 1997 • California
RECITALS --------Medical Science Systems Inc • October 8th, 1997 • California
1 EXHIBIT 4.6 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR ANY STATE SECURITIES LAWS. THIS WARRANT MAY NOT BE TRANSFERRED IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS AN EXEMPTION THEREFROM IS AVAILABLE....Medical Science Systems Inc • October 8th, 1997
November 9, 1994Medical Science Systems Inc • October 8th, 1997
