0000927016-03-002603 Sample Contracts

Amended and Restated as of February 27 , 2003 Mr. Stephen Cohen Arlington, MA 02474 Dear Stephen:
Employment Agreement • May 13th, 2003 • Genome Therapeutics Corp • In vitro & in vivo diagnostic substances • Massachusetts

This letter will confirm our offer to you of employment with Genome Therapeutics Corp. (the “Company”), under the terms and conditions that follow:

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March 31, 2003 EMPLOYMENT AGREEMENT Martin D. Williams Watertown, MA 02472 Dear Martin:
Employment Agreement • May 13th, 2003 • Genome Therapeutics Corp • In vitro & in vivo diagnostic substances • Massachusetts

This letter will confirm our offer to you of employment with Genome Therapeutics Corp. (the “Company”), under the terms and conditions that follow:

Genome Therapeutics Corp. March 12, 2003
Retirement Agreement • May 13th, 2003 • Genome Therapeutics Corp • In vitro & in vivo diagnostic substances

The purpose of this letter (the “Agreement”) is to confirm the agreement between you and Genome Therapeutics Corp. (the “Company”) concerning your retirement as an employee of the Company, as follows:

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