0000932683-01-500002 Sample Contracts

JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Sub-Investment Management Contract Dated May11, 2001 JOHN HANCOCK ADVISERS, INC. 101 Huntington Avenue Boston, Massachusetts 02199 JOHN HANCOCK INSTITUTIONAL SERIES TRUST -...
Sub-Investment Management Contract • October 29th, 2001 • Hancock John Institutional Series Trust • Massachusetts

JOHN HANCOCK INSTITUTIONAL SERIES TRUST John Hancock International Equity Fund Sub-Investment Management Contract Dated May11, 2001 JOHN HANCOCK ADVISERS, INC. 101 Huntington Avenue Boston, Massachusetts 02199 JOHN HANCOCK INSTITUTIONAL SERIES TRUST - John Hancock International Equity Fund 101 Huntington Avenue Boston, Massachusetts 02199 NICHOLAS-APPLEGATE CAPITAL MANAGEMENT 600 West Broadway San Diego, California 92101 Sub-Investment Management Contract Ladies and Gentlemen: John Hancock Institutional Series Trust (the "Trust") has been organized as a business trust under the laws of The Commonwealth of Massachusetts to engage in the business of an investment company. The Trust's shares of beneficial interest may be classified into series, each series representing the entire undivided interest in a separate portfolio of assets. Series may be established or terminated from time to time by action of the Board of Trustees of the Trust. As of the date hereof, the Trust has eleven series

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