0000950123-09-032050 Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. TECHNOLOGY AND TRADEMARK LICENSE AGREEMENT
Technology and Trademark License Agreement • August 7th, 2009 • NxStage Medical, Inc. • Electromedical & electrotherapeutic apparatus • New York

THIS TECHNOLOGY AND TRADEMARK LICENSE AGREEMENT (the “Agreement”), dated as of June 5, 2009 (the “Effective Date”), is made and entered into by and between NxStage Medical, Inc., a company organized and existing under the laws of Delaware, and having offices at 439 S. Union Street, 5th Floor, Lawrence, Massachusetts 01843, United States of America, (hereafter referred to as “NxStage”) and Asahi Kasei Kuraray Medical, Co., Ltd., a corporation organized and existing under the law of Japan, having its principal place of business at 1-105, Kanda Jinbocho, Chiyoda-ku, Tokyo 101-8101, Japan (hereafter referred to as “Asahi”). NxStage and Asahi are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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EXTRACORPOREAL DISPOSABLES DISTRIBUTION AGREEMENT
Extracorporeal Disposables Distribution Agreement • August 7th, 2009 • NxStage Medical, Inc. • Electromedical & electrotherapeutic apparatus

This Agreement, dated as of June 15, 2009 (the “Effective Date”), is between Medisystems Corporation, a Washington corporation with offices at 439 South Union Street, 5th Floor, Lawrence, Massachusetts 10843 (together with its affiliates, “MDS”) and Gambro Renal Products, Inc., a Colorado corporation with offices at 14143 Denver West Parkway, Lakewood, Colorado 80401 (together with its affiliates, “Gambro”). MDS and Gambro shall each be referred to herein as a “Party” and collectively as the “Parties”.

TERM LOAN AND SECURITY AGREEMENT
Term Loan and Security Agreement • August 7th, 2009 • NxStage Medical, Inc. • Electromedical & electrotherapeutic apparatus • New York

THIS TERM LOAN AND SECURITY AGREEMENT (as the same may be amended, supplemented, restated or otherwise modified from time to time, the “Agreement”), dated as of , 2009 (“Effective Date”), is made and entered into by and among (a) NxStage Medical, Inc., a company organized and existing under the laws of Delaware, United States of America (“NxStage Medical”), EIR Medical, Inc. (“EIR”), a company organized and existing under the laws of Massachusetts, United States of America, Medisystems Services Corporation (“Medisystems Services”), a company organized and existing under the laws of Nevada, United States of America, Medisystems Corporation (“Medisystems”), a company organized and existing under the laws of Washington, United States of America, each as a borrower hereunder (NxStage Medical, EIR, Medisystems Services, and Medisystems being referred to collectively herein as the “Borrowers” and each as a “Borrower”); (b) Medimexico s. de R.L. de C.V., a company organized and existing under

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisk denote omissions. SUPPLY AGREEMENT
Supply Agreement • August 7th, 2009 • NxStage Medical, Inc. • Electromedical & electrotherapeutic apparatus • Massachusetts

THIS SUPPLY AGREEMENT (this “Agreement”) is dated as of April 10, 2009 (“Effective Date”), and is by and between Laboratorios PiSA S.A. de C.V., a corporation organized under the laws of Mexico having offices at Calle 7 No. 1308 Zona Industrial, C.P. 44940 Guadalajara, Jal., Mexico (“PiSA”) and NxStage Medical, Inc., a Delaware corporation, having office at 439 South Union Street, 5th Floor, Lawrence, Massachusetts 01843, USA (“NxStage”).

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