0000950134-05-023806 Sample Contracts

AMENDMENT TO CORE DISTRIBUTION AGREEMENT
Core Distribution Agreement • December 23rd, 2005 • Connetics Corp • Pharmaceutical preparations

THIS AMENDMENT TO CORE DISTRIBUTION AGREEMENT (“Amendment”) is entered into as of December 22, 2005 (the “Effective Date”), by and between Connetics Corporation (“Connetics”) and McKesson Corporation (“McKesson”). Connetics and McKesson entered into a Core Distribution Agreement dated December 23, 2004 (“Agreement”). Capitalized terms not defined herein shall have the meaning ascribed to such terms in the Agreement. The Parties desire to amend the Agreement in the manner set forth in this Amendment.

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AMENDMENT TO DISTRIBUTION AGREEMENT
Distribution Agreement • December 23rd, 2005 • Connetics Corp • Pharmaceutical preparations

THIS AMENDMENT TO DISTRIBUTION AGREEMENT (“Amendment”) is entered into as of December 22, 2005 (the “Effective Date”), by and between Connetics Corporation (“Connetics”) and Cardinal Health, Inc. (“Cardinal”). Connetics and Cardinal entered into a Distribution Agreement dated December 1, 2004 (“Agreement”). The Parties desire to amend the Agreement in the manner set forth in this Amendment. Capitalized terms not otherwise defined herein shall have the meaning ascribed to such terms in the Agreement.

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