Core Distribution Agreement Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. McKesson Corporation Core Distribution Agreement
Core Distribution Agreement • April 4th, 2008 • Xanodyne Pharmaceuticals Inc • Pharmaceutical preparations • California

This Core Distribution Agreement (“Agreement”) is entered into as of November 1 , 2005 (the “Effective Date”) between McKesson Corporation (“McKesson”), a pharmaceutical distributor, and Xanodyne Pharmaceuticals, Inc. (“Manufacturer”), a pharmaceutical company.

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AMENDMENT TO CORE DISTRIBUTION AGREEMENT
Core Distribution Agreement • December 23rd, 2005 • Connetics Corp • Pharmaceutical preparations

THIS AMENDMENT TO CORE DISTRIBUTION AGREEMENT (“Amendment”) is entered into as of December 22, 2005 (the “Effective Date”), by and between Connetics Corporation (“Connetics”) and McKesson Corporation (“McKesson”). Connetics and McKesson entered into a Core Distribution Agreement dated December 23, 2004 (“Agreement”). Capitalized terms not defined herein shall have the meaning ascribed to such terms in the Agreement. The Parties desire to amend the Agreement in the manner set forth in this Amendment.

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SECOND AMENDMENT TO CORE DISTRIBUTION AGREEMENT
Core Distribution Agreement • October 17th, 2006 • Connetics Corp • Pharmaceutical preparations

THIS SECOND AMENDMENT TO CORE DISTRIBUTION AGREEMENT (“Second Amendment”) is entered into as of October 11, 2006, by and between Connetics Corporation (“Connetics”) and McKesson Corporation (“McKesson”). Connetics and McKesson entered into a Core Distribution Agreement dated December 23, 2004 (“Original Agreement”), as amended by that certain Amendment to Core Distribution Agreement dated as of December 22, 2005 (“First Amendment”; the Original Agreement together with the First Amendment shall hereinafter be collectively referred to as the “Agreement”). Capitalized terms not defined herein shall have the meaning ascribed to such terms in the Agreement.

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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. McKesson Corporation Core Distribution Agreement
Core Distribution Agreement • May 5th, 2005 • Collagenex Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

This Core Distribution Agreement (“Agreement”) is entered into between McKesson Corporation (“McKesson”), a pharmaceutical distributor, and CollaGenex Pharmaceuticals (“Manufacturer”), a pharmaceutical manufacturer.

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BACKGROUND
Core Distribution Agreement • March 16th, 2005 • Connetics Corp • Pharmaceutical preparations
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