0000950134-06-019189 Sample Contracts

SECOND AMENDMENT TO CORE DISTRIBUTION AGREEMENT
Core Distribution Agreement • October 17th, 2006 • Connetics Corp • Pharmaceutical preparations

THIS SECOND AMENDMENT TO CORE DISTRIBUTION AGREEMENT (“Second Amendment”) is entered into as of October 11, 2006, by and between Connetics Corporation (“Connetics”) and McKesson Corporation (“McKesson”). Connetics and McKesson entered into a Core Distribution Agreement dated December 23, 2004 (“Original Agreement”), as amended by that certain Amendment to Core Distribution Agreement dated as of December 22, 2005 (“First Amendment”; the Original Agreement together with the First Amendment shall hereinafter be collectively referred to as the “Agreement”). Capitalized terms not defined herein shall have the meaning ascribed to such terms in the Agreement.

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AMENDMENT TO DISTRIBUTION SERVICES AGREEMENT
Distribution Services Agreement • October 17th, 2006 • Connetics Corp • Pharmaceutical preparations

THIS AMENDMENT TO DISTRIBUTION SERVICES AGREEMENT (“Amendment”) is entered into as of October 11, 2006, by and between Connetics Corporation (“Connetics”) and AmerisourceBergen Drug Corporation (“AmerisourceBergen”). Connetics and AmerisourceBergen entered into that certain Distribution Services Agreement dated September 30, 2005 (“Agreement”). Capitalized terms not defined herein shall have the meaning ascribed to such terms in the Agreement. The Parties desire to amend the Agreement as set forth below.

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