0000950135-08-006444 Sample Contracts

AMENDMENT NO. 1 TO STOCKHOLDER RIGHTS AGREEMENT
Stockholder Rights Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

This Amendment No. 1 to Stockholder Rights Agreement (the “Amendment”), dated as of October 1, 2008, by and between OXiGENE, Inc., a Delaware corporation (the “Company”), and American Stock Transfer & Trust Company (the “Rights Agent”), amends that certain Stockholder Rights Agreement, dated as of March 24, 2005, between the Company and the Rights Agent (the “Agreement”).

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TECHNOLOGY LICENSE AGREEMENT between OXiGENE, INC., and SYMPHONY ViDA HOLDINGS LLC Dated as of October 1, 2008
Technology License Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

This TECHNOLOGY LICENSE AGREEMENT (this “Agreement”) is made and effective as of October 1, 2008 by and among OXiGENE, Inc., a Delaware corporation (the “Licensor”) and Symphony ViDA Holdings LLC, a Delaware limited liability company (“Holdings”).

ADDITIONAL FUNDING AGREEMENT
Additional Funding Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

This ADDITIONAL FUNDING AGREEMENT (this “Agreement”) is entered into as of October 1, 2008, by and among OXiGENE, INC., a Delaware corporation (the “Company”), SYMPHONY ViDA HOLDINGS LLC, a Delaware limited liability company (“Holdings”), SYMPHONY ViDA INVESTORS LLC, a Delaware limited liability company (“Investors”), and SYMPHONY ViDA, INC., a Delaware corporation (the “Symphony Collaboration”).

PURCHASE OPTION AGREEMENT by and among OXiGENE, INC. SYMPHONY ViDA HOLDINGS LLC and SYMPHONY ViDA, INC.
Purchase Option Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

This PURCHASE OPTION AGREEMENT (this “Agreement”) is entered into as of October 1, 2008 (the “Closing Date”), by and among OXiGENE, INC., a Delaware corporation (the “Company”), SYMPHONY ViDA HOLDINGS LLC, a Delaware limited liability company (“Holdings”), and SYMPHONY ViDA, INC., a Delaware corporation (the “Symphony Collaboration”). Capitalized terms used herein and not defined herein shall have the meanings assigned to such terms in Annex A attached hereto.

STOCK AND WARRANT PURCHASE AGREEMENT between OXiGENE, INC. and SYMPHONY ViDA HOLDINGS LLC Dated as of October 1, 2008
Stock and Warrant Purchase Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • New York

Portions of this Exhibit were omitted and have been filed separately with the Secretary of the Commission pursuant to the Company’s application requesting confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

NOVATED AND RESTATED TECHNOLOGY LICENSE AGREEMENT among OXiGENE, INC., SYMPHONY ViDA, INC. and SYMPHONY ViDA HOLDINGS LLC Dated as of October 1, 2008
Novated and Restated Technology License Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

This NOVATED AND RESTATED TECHNOLOGY LICENSE AGREEMENT (this “Agreement”) is made and effective as of October 1, 2008 by and among OXiGENE, Inc., a Delaware corporation (the “Licensor”), Symphony ViDA, Inc., a Delaware corporation (the “Symphony Collaboration”) (each of Licensor and the Symphony Collaboration being a “Party,” and collectively, the “Parties”), and Symphony ViDA Holdings LLC, a Delaware limited liability company (“Holdings”).

REGISTRATION RIGHTS AGREEMENT between OXiGENE, INC. and SYMPHONY ViDA HOLDINGS LLC Dated as of October 1, 2008
Registration Rights Agreement • October 10th, 2008 • Oxigene Inc • Biological products, (no disgnostic substances) • Delaware

REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of October 1, 2008, by and between OXiGENE, INC., a Delaware corporation (the “Company”), and SYMPHONY ViDA HOLDINGS LLC, a Delaware limited liability company (together with its permitted successors, assigns and transferees, “Holdings”).

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