0000950144-09-001988 Sample Contracts

SEVERANCE AGREEMENT AND GENERAL RELEASE
Severance Agreement • March 6th, 2009 • Biocryst Pharmaceuticals Inc • Biological products, (no disgnostic substances)

This SEVERANCE AGREEMENT AND GENERAL RELEASE (“Agreement”) is made and entered into by Michael Darwin (“Employee”) and BioCryst Pharmaceuticals, Inc. (“the Company”).

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FIRST AMENDMENT TO LICENSE, DEVELOPMENT AND COMMERCIALIZATION AGREEMENT
License, Development and Commercialization Agreement • March 6th, 2009 • Biocryst Pharmaceuticals Inc • Biological products, (no disgnostic substances) • New York

This First Amendment (this “Amendment”) to the License, Development and Commercialization Agreement between BioCryst Pharmaceuticals, Inc. (“BioCryst”) and Shionogi & Co., Ltd. (“Shionogi”), dated as of February 28, 2007 (the “Agreement”), shall be effective as of September 30, 2008 (the “First Amendment Date”).

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