0001010521-07-000734 Sample Contracts

JOHN HANCOCK INSTITUTIONAL SERIES TRUST SUB-INVESTMENT MANAGEMENT CONTRACT
John Hancock Institutional Series Trust • October 26th, 2007 • Hancock John Institutional Series Trust • Massachusetts

AGREEMENT made this 14th day of July, 2006, among John Hancock Advisers, LLC, a Delaware limited liability company (the “Adviser”), Independence Investments, LLC a Delaware limited liability company (the “Sub-adviser”) and John Hancock Institutional Series Trust, a business trust under the laws of the Commonwealth of Massachusetts (the “Trust”) on behalf of the John Hancock Independence Diversified Core Equity Fund II (the “Fund”), a series of the Trust. In consideration of the mutual covenants contained herein, the parties agree as follows:

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