Exhibit 10.5.1 FIRST AMENDMENT TO LEASE This FIRST AMENDMENT TO LEASE (this "First Amendment") is executed by and between KS Parcel D, LLC (the "Landlord"), a Delaware limited liability company, and Genzyme Corporation (the "Tenant"). Reference is...Lease • March 15th, 2005 • Genzyme Corp • Biological products, (no disgnostic substances)
BY AND BETWEENNorth American Termination and Transition Agreement • March 15th, 2005 • Genzyme Corp • Biological products, (no disgnostic substances) • Massachusetts
FOURTH AMENDMENT CONTRACT MANUFACTURING AGREEMENTFourth Amendment Contract Manufacturing Agreement • March 15th, 2005 • Genzyme Corp • Biological products, (no disgnostic substances)
