LICENSE AND CO-DEVELOPMENT AGREEMENT BY AND BETWEEN GENZYME CORPORATION AND ISIS PHARMACEUTICALS, INC. June 24, 2008Supply Agreement • August 11th, 2008 • Genzyme Corp • Biological products, (no disgnostic substances) • New York
Contract Type FiledAugust 11th, 2008 Company Industry JurisdictionThis License and Co-Development Agreement (together with all Exhibits, Schedules and other attachments hereto, this “Agreement”), is dated as of the 24th day of June, 2008 (the “Execution Date”), by and between Genzyme Corporation, a Massachusetts corporation (“Genzyme”) and Isis Pharmaceuticals, Inc., a Delaware corporation (“Isis”). Genzyme and Isis each may be referred to herein individually as a “Party” or collectively as the “Parties.”