FIFTY NORTHERN AVENUE LLC AND VERTEX PHARMACEUTICALS INCORPORATED LEASE FOR 50 NORTHERN AVENUE (PARCEL A — FAN PIER) BOSTON, MASSACHUSETTSLease Agreement • August 9th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
Confidential Treatment Requested Confidential portions of this document have been redacted and have been separately filed with the Commission RESEARCH, DEVELOPMENT AND COMMERCIALIZATION AGREEMENT between Vertex Pharmaceuticals Incorporated and Cystic...Research, Development and Commercialization Agreement • August 9th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
This Agreement is a modification and continuation of a relationship originally set forth in an earlier Cystic Fibrosis Research Alliance and Commercialization Agreement dated as of May 19, 2000 (the “Original Agreement”), between the Cystic Fibrosis Foundation, which is an Affiliate of CFFT, and Aurora Biosciences Corporation, which was acquired by Vertex in 2001. Except as specifically provided herein, this Agreement supercedes in its entirety the Original Agreement which shall be of no further force and effect.
LICENSE AND COLLABORATION AGREEMENT BY AND BETWEEN ALIOS BIOPHARMA, INC. AND VERTEX PHARMACEUTICALS INCORPORATED AND VERTEX PHARMACEUTICALS (SWITZERLAND) LLC DATED June 13, 2011License and Collaboration Agreement • August 9th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • New York
THIS LICENSE AND COLLABORATION AGREEMENT (this “Agreement”) is entered into on June 13, 2011 (“Execution Date”) by and between Alios BioPharma, Inc., a corporation organized under the laws of the State of Delaware, having offices at 260 East Grand Avenue, 2nd Floor, South San Francisco, California 94080, United States of America (“Alios”) and Vertex Pharmaceuticals Incorporated, a Massachusetts corporation having offices at 130 Waverly Street, Cambridge, Massachusetts 02139, United States of America, and its wholly-owned subsidiary Vertex Pharmaceuticals (Switzerland) LLC (together, “Vertex”). Alios and Vertex are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”
Confidential Treatment Requested Confidential portions of this document have been redacted and have been separately filed with the Commission AMENDMENT NO. 5 to RESEARCH, DEVELOPMENT AND COMMERCIALIZATION AGREEMENT, DATED MAY 24, 2004, by and between...Research, Development and Commercialization Agreement • August 9th, 2011 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations
This Amendment No. 5 (the “Fifth Amendment”) is made effective as of April 1, 2011 (the “Effective Date”) by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation with its principal offices at 130 Waverly Street, Cambridge, Massachusetts 02139-4242 (“Vertex”), and Cystic Fibrosis Foundation Therapeutics Incorporated, a Delaware corporation with its principal offices at 6931 Arlington Road, Bethesda, Maryland 20814 (“CFFT”).
