0001047469-12-001298 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • February 22nd, 2012 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This Employment Agreement (this “Agreement”) is made and entered into as of this 31st day of January, 2012, by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation (together with its successors and assigns, the “Company”), and Christiana Stamoulis (the “Executive”).

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VERTEX PHARMACEUTICALS INCORPORATED
Change of Control Agreement • February 22nd, 2012 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts
EMPLOYEE NON-DISCLOSURE, NON-COMPETITION & INVENTIONS AGREEMENT
Employee Non-Disclosure, Non-Competition & Inventions Agreement • February 22nd, 2012 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This Agreement made and entered into in Cambridge, Massachusetts, by Jeffrey M. Leiden, M.D., Ph.D. (the “Executive”) and Vertex Pharmaceuticals Incorporated (the “Company”), effective as of the Executive’s first day of employment with the Company, on the 14th day of December, 2011.

Confidential Treatment Requested. Confidential portions of this document have been redacted and have been separately filed with the Commission. LICENSE, DEVELOPMENT, MANUFACTURING AND COMMERCIALIZATION AGREEMENT by and between Vertex Pharmaceuticals...
License, Development, Manufacturing and Commercialization Agreement • February 22nd, 2012 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

This License, Development, Manufacturing and Commercialization Agreement (this “Agreement”) is effective as of June 30, 2006 (the “Effective Date”) and is entered into by and between Vertex Pharmaceuticals Incorporated, a Massachusetts corporation with corporate offices at 130 Waverly Street, Cambridge, MA 02139-4242, United States of America (“Vertex”) and Janssen Pharmaceutica, N.V., a Belgium corporation with corporate offices at 30, Turnhoutsesteenweg, B-2340 Beerse, Belgium (“Janssen”).

AGREEMENT
Employment Agreement • February 22nd, 2012 • Vertex Pharmaceuticals Inc / Ma • Pharmaceutical preparations • Massachusetts

AGREEMENT made and entered into in Cambridge, Massachusetts, by and between Vertex Pharmaceuticals Incorporated (the “Company”) and Jeffrey M. Leiden, MD., Ph.D. (the “Executive”), effective as of the 14th day of December, 2011.

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