0001062993-05-000486 Sample Contracts

Response Biomedical Signs Agency Agreement, Amends Proposed Financing
Agency Agreement • March 11th, 2005 • Response Biomedical Corp • Services-testing laboratories

Vancouver, British Columbia, December 20, 2004 – Response Biomedical Corp. (TSX-V: RBM), today announced it has signed an agency agreement with Haywood Securities Inc. relating to the proposed best efforts private placement announced November 15, 2004. Based on the level of interest received to date, the Company has increased the upper limit of the financing from $1.5 to $3.0 million. Up to 4,000,000 Units are to be placed at a price $0.75 per Unit, each Unit consisting of one common share and two non-transferable one-half of one common share purchase warrants.

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