0001078782-08-000146 Sample Contracts

AMENDMENT NO. 4 TO SECURITIES EXCHANGE AGREEMENT
Securities Exchange Agreement • January 31st, 2008 • RNS Software, Inc. • Services-prepackaged software

Amendment No. 4 (the “Amendment No. 4”), dated as of January 28, 2008, to the Securities Exchange Agreement (as amended by Amendments dated as of July 30, 2007, August 29, 2007, and October 31, 2007, the “Exchange Agreement”), dated as of April 30, 2007, entered into by and among RNS Software, Inc., a Nevada corporation (“RNS”), Livio Susin (“Susin”), Regena Therapeutics, Inc., a Delaware corporation (“Regena”), and the shareholders of Regena (“Regena Shareholders”).

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