0001104659-06-051384 Sample Contracts

August 3, 2006 Leslie J. Browne, Ph.D.
Employment Agreement • August 4th, 2006 • Pharmacopeia Drug Discovery Inc • Services-commercial physical & biological research

Re: Amendment to Employment Agreement amended and restated as of February 27, 2006 between Pharmacopeia Drug Discovery, Inc. (“Pharmacopeia”) and Leslie Johnston Browne, Ph.D. (the “Agreement”)

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August 3, 2006 Brian M. Posner
Severance Agreement • August 4th, 2006 • Pharmacopeia Drug Discovery Inc • Services-commercial physical & biological research

Re: Amendment to Severance Agreement dated May 4, 2006 between Pharmacopeia Drug Discovery, Inc. (“Pharmacopeia”) and Brian M. Posner (the “Agreement”)

August 3, 2006 Stephen C. Costalas, Esq.
Pharmacopeia Drug Discovery Inc • August 4th, 2006 • Services-commercial physical & biological research

Re: Amendment to Severance Agreement dated December 2, 2004 and amended November 3, 2005 between Pharmacopeia Drug Discovery, Inc. (“Pharmacopeia”) and Stephen C. Costalas (the “Agreement”)

August 3, 2006 David M. Floyd, Ph.D.
Pharmacopeia Drug Discovery Inc • August 4th, 2006 • Services-commercial physical & biological research

Re: Amendment to Severance Agreement dated December 2, 2004 and amended November 3, 2005 between Pharmacopeia Drug Discovery, Inc. (“Pharmacopeia”) and David M. Floyd (the “Agreement”)

COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • August 4th, 2006 • Pharmacopeia Drug Discovery Inc • Services-commercial physical & biological research • Delaware

This COLLABORATION AND LICENSE AGREEMENT (the “Agreement”), effective as of May 18th, 2006 (the “Effective Date”), is made by and between Pharmacopeia Drug Discovery, Inc., a Delaware corporation, having a principal place of business at 3000 Eastpark Boulevard, Cranbury, New Jersey 08512 (“Pharmacopeia”), and Cephalon, Inc., a Delaware corporation, having a principal place of business at 41 Moores Road, Frazer, PA 19355 (“Cephalon”).

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