0001104659-07-041422 Sample Contracts

WARRANT AGENT AGREEMENT
Warrant Agent Agreement • May 18th, 2007 • Progen Pharmaceuticals LTD • Medicinal chemicals & botanical products • Colorado

Progen Pharmaceuticals Limited, an Australia corporation (the “Company”), Computershare, Inc., a Delaware corporation, and its fully owned subsidiary Computershare Trust Company, N.A. a federally chartered trust company, having its principal office at 250 Royall Street, Canton, MA 02021 (collectively “Warrant Agent” or individually “Computershare” and the “Trust Company,” respectively), agree as follows:

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SUBSCRIPTION AGENT AGREEMENT
Subscription Agent Agreement • May 18th, 2007 • Progen Pharmaceuticals LTD • Medicinal chemicals & botanical products • Massachusetts

This Subscription Agent Agreement (the “Agreement”) is made as of May 15, 2007 between Progen Pharmaceuticals Limited, an Australia Corporation (the “Company”), Computershare, Inc., a Delaware corporation and its fully owned subsidiary Computershare Trust Company, N.A., a federally chartered trust company (collectively, the “Agent” or individually “Computershare” and the “Trust Company,” respectively). All terms not defined herein shall have the meaning given in the prospectus dated April 13, 2007 and in the preliminary prospectus supplement dated May 10, 2007 (together, the “Prospectus”) included in the Registration Statement on Form F-3, File No. 333-141489 filed by the Company with the Securities and Exchange Commission on March 22, 2007, as amended by any amendment filed with respect thereto (the “Registration Statement”).

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