0001104659-07-059116 Sample Contracts

METABASIS THERAPEUTICS, INC. SEVERANCE AGREEMENT
Severance Agreement • August 6th, 2007 • Metabasis Therapeutics Inc • Pharmaceutical preparations • California

THIS SEVERANCE AGREEMENT (this “Agreement”) is entered into effective as of April 27, 2007 (the “Effective Date”), by and between MARK D. ERION (the “Employee”) and METABASIS THERAPEUTICS, INC., a Delaware corporation (the “Company”).

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FIRST AMENDMENT TO AMENDED AND RESTATED SEVERANCE AGREEMENT
Severance Agreement • August 6th, 2007 • Metabasis Therapeutics Inc • Pharmaceutical preparations • California

This FIRST AMENDMENT TO AMENDED AND RESTATED SEVERANCE AGREEMENT (“First Amendment”) is entered into on April 27, 2007, by and between METABASIS THERAPEUTICS, INC., a Delaware corporation (the “Company”), and PAUL K. LAIKIND (the “Employee”). Capitalized terms used and not otherwise defined herein shall have the meanings ascribed to such terms in the Severance Agreement (as defined below).

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