0001104659-08-065777 Sample Contracts

LICENSE AGREEMENT
License Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware
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NOTE PURCHASE AGREEMENT BY AND BETWEEN ACUSPHERE, INC. AND CEPHALON, INC. DATED: OCTOBER 24, 2008
Assignment Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

NOTE PURCHASE AGREEMENT, dated as of October 24, 2008 (this “Agreement”), by and between Cephalon, Inc., a Delaware corporation (the “Purchaser”), and Acusphere, Inc., a Delaware corporation (the “Company”).

REGISTRATION RIGHTS AGREEMENT by and between ACUSPHERE, INC., and CEPHALON, INC. dated as of
Registration Rights Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware
PLEDGE AND SECURITY AGREEMENT
Pledge and Security Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

THIS PLEDGE AND SECURITY AGREEMENT (as the same may be amended, restated, supplemented or otherwise modified from time to time, this “Security Agreement”) is entered into as of November [ ], 2008 by and between ACUSPHERE, INC., a Delaware corporation (the “Grantor”), and CEPHALON, INC., a Delaware corporation (the “Secured Party”).

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