0001104659-08-065777 Sample Contracts

LICENSE AGREEMENT

License Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

• Contract Type
  License Agreement
• Filed
  October 27th, 2008
• Company
  Acusphere Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

NOTE PURCHASE AGREEMENT BY AND BETWEEN ACUSPHERE, INC. AND CEPHALON, INC. DATED: OCTOBER 24, 2008

Note Purchase Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

• Contract Type
  Note Purchase Agreement
• Filed
  October 27th, 2008
• Company
  Acusphere Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

NOTE PURCHASE AGREEMENT, dated as of October 24, 2008 (this “Agreement”), by and between Cephalon, Inc., a Delaware corporation (the “Purchaser”), and Acusphere, Inc., a Delaware corporation (the “Company”).

REGISTRATION RIGHTS AGREEMENT by and between ACUSPHERE, INC., and CEPHALON, INC. dated as of

Registration Rights Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

• Contract Type
  Registration Rights Agreement
• Filed
  October 27th, 2008
• Company
  Acusphere Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

PLEDGE AND SECURITY AGREEMENT

Pledge and Security Agreement • October 27th, 2008 • Acusphere Inc • Pharmaceutical preparations • Delaware

• Contract Type
  Pledge and Security Agreement
• Filed
  October 27th, 2008
• Company
  Acusphere Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

THIS PLEDGE AND SECURITY AGREEMENT (as the same may be amended, restated, supplemented or otherwise modified from time to time, this “Security Agreement”) is entered into as of November [ ], 2008 by and between ACUSPHERE, INC., a Delaware corporation (the “Grantor”), and CEPHALON, INC., a Delaware corporation (the “Secured Party”).