Exhibit 10.25 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE, OFFER FOR SALE, PLEDGE, HYPOTHECATION OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS...Acusphere Inc • July 1st, 2003 • Pharmaceutical preparations • Delaware
Company FiledJuly 1st, 2003 Industry Jurisdiction
RECITALS:Securities Purchase Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
LICENSE AGREEMENT BY AND BETWEEN ACUSPHERE, INC. ANDLicense Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
ACUSPHERE, INC.Acusphere Inc • September 4th, 2001 • Massachusetts
Company FiledSeptember 4th, 2001 Jurisdiction
CONFIDENTIAL TREATMENT REQUESTED] /*/ INDICATES MATERIAL THAT HAS BEEN OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED. ALL SUCH OMITTED MATERIAL HAS BEEN FILED WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 406...Termination Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
Exhibit 10.26 THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE, OFFER FOR SALE, PLEDGE, HYPOTHECATION OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS...Acusphere Inc • July 1st, 2003 • Pharmaceutical preparations • Delaware
Company FiledJuly 1st, 2003 Industry Jurisdiction
Exhibit 10.33 [ACUSPHERE, INC. LETTERHEAD] ACUSPHERE THIS CONSULTING AGREEMENT (the "Agreement"), made as of the 21th Day of May, 1999, is entered into by and between Acusphere, Inc., a Delaware corporation with its principal place of business at 38...Consulting Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
Exhibit 10.25 ACUSPHERE NEWCO, LTD. REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (the "Agreement") is made as of June 30, 2000 by and among ACUSPHERE NEWCO, LTD., a Bermuda exempted limited liability company (the "Company"),...Registration Rights Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
EXHIBIT 10.26 EXCHANGE AGREEMENT This Exchange Agreement is made as of the 30th of June, 2000 (the "Effective Date") by and among Acusphere, Inc., a Delaware corporation ("Acusphere"), and Elan International Services, Ltd., a Bermuda exempted limited...Exchange Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
Exhibit 10.04 AMENDED AND RESTATED STOCKHOLDERS' AGREEMENT THIS AGREEMENT, made as of the 24th day of January, 1994, by and among Polymers for Medicine, Inc., a Delaware corporation (the "Company"), and Robert S. Langer ("Langer"), Sherri C. Oberg...Stockholders' Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
Exhibit 10.20 LEASE AGREEMENT THIS LEASE AGREEMENT is made this 30th day of March, 2001, between ARE-500 ARSENAL STREET, LLC, a Delaware limited liability company ("LANDLORD"), and ACUSPHERE, INC., a Delaware corporation ("TENANT"). ADDRESS: 500...Lease Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations
Contract Type FiledJuly 1st, 2003 Company Industry
Exhibit 10.13 THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL...Warrant Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
COMMON STOCKUnderwriting Agreement • October 6th, 2003 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 6th, 2003 Company Industry Jurisdiction
1 Exhibit 10.07 EIGHTH AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT ACUSPHERE, INC. June 1, 2001 TABLE OF CONTENTSInvestors' Rights Agreement • September 4th, 2001 • Acusphere Inc • Massachusetts
Contract Type FiledSeptember 4th, 2001 Company Jurisdiction
Exhibit 10.29 THIS WARRANT AND THE SECURITIES THAT MAY BE ACQUIRED UPON EXERCISE OF THE WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NEITHER THIS WARRANT NOR THE SECURITIES THAT MAY BE ACQUIRED UPON EXERCISE OF THIS...Acusphere Inc • July 1st, 2003 • Pharmaceutical preparations • Massachusetts
Company FiledJuly 1st, 2003 Industry Jurisdiction
Exhibit 10.09 THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL...Warrant Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
WITNESSETHAcusphere Inc • November 3rd, 2004 • Pharmaceutical preparations
Company FiledNovember 3rd, 2004 Industry
EXHIBIT 10.30 ACUSPHERE, INC. INDEMNIFICATION AGREEMENT This Indemnification Agreement (the "Agreement") is made as of August __, 2003, by and between Acusphere, Inc., a Delaware corporation (the "Company"), and _____________ (the "Indemnitee")....Indemnification Agreement • August 6th, 2003 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledAugust 6th, 2003 Company Industry Jurisdiction
SUBLEASESublease • September 4th, 2001 • Acusphere Inc • Massachusetts
Contract Type FiledSeptember 4th, 2001 Company Jurisdiction
EXECUTION COPY ACUSPHERE, INC. INDEMNIFICATION AGREEMENT This Indemnification Agreement (the "Agreement") is made as of August __, 2002, by and between Acusphere, Inc., a Delaware corporation (the "Company"), and _____________ (the "Indemnitee")....Indemnification Agreement • August 6th, 2003 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledAugust 6th, 2003 Company Industry Jurisdiction
WITNESSETH THATDevelopment and Supply Agreement • September 12th, 2003 • Acusphere Inc • Pharmaceutical preparations • Washington
Contract Type FiledSeptember 12th, 2003 Company Industry Jurisdiction
7,694,220 Shares and Warrants to Purchase 3,077,688 Shares ACUSPHERE, INC. Common Stock ($.01 par value) PLACEMENT AGENT AGREEMENTPlacement Agent Agreement • June 12th, 2007 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledJune 12th, 2007 Company Industry Jurisdiction
EXECUTION COPY ACUSPHERE, INC. INDEMNIFICATION AGREEMENT This Indemnification Agreement (the "Agreement") is made as of August __, 2002, by and between Acusphere, Inc., a Delaware corporation (the "Company"), and _____________ (the "Indemnitee")....Indemnification Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
ACUSPHERE, INC.Acusphere Inc • July 1st, 2003 • Pharmaceutical preparations • Delaware
Company FiledJuly 1st, 2003 Industry Jurisdiction
COMMON STOCK PURCHASE AGREEMENTCommon Stock Purchase Agreement • September 1st, 2006 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledSeptember 1st, 2006 Company Industry JurisdictionThis COMMON STOCK PURCHASE AGREEMENT, made and entered into on this 31st day of August 2006 (this “Agreement”), by and between Azimuth Opportunity Ltd., an international business company incorporated under the laws of the British Virgin Islands (the “Investor”), and Acusphere, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”).
RECITALSSubordinated Loan and Security Agreement • September 4th, 2001 • Acusphere Inc • Illinois
Contract Type FiledSeptember 4th, 2001 Company Jurisdiction
Exhibit 10.16 THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL...Warrant Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
DEBT SECURITIES COMMON STOCK PREFERRED STOCK WARRANTSUnderwriting Agreement • December 23rd, 2004 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 23rd, 2004 Company Industry Jurisdiction
EXECUTION COPY ACUSPHERE, INC. INDEMNIFICATION AGREEMENT This Indemnification Agreement (the "AGREEMENT") is made as of ___________ __, 2004, by and between Acusphere, Inc., a Delaware corporation (the "COMPANY"), and _________________ (the...Indemnification Agreement • September 15th, 2004 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledSeptember 15th, 2004 Company Industry Jurisdiction
AND ACUSPHERE, INC. ANDJoint Development and Operating Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
Exhibit 10.42 ACUSPHERE, INC. INCENTIVE STOCK OPTION AGREEMENT Acusphere, Inc., a Delaware corporation (the "Corporation"), hereby grants this 26th day of , 2001 to James R Fitzgerald, Jr. (the "Optionee"), an option to purchase a maximum of 275,000...Incentive Stock Option Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • Delaware
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction
EXHIBIT 10.07 TENTH AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT' Rights Agreement • September 12th, 2003 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledSeptember 12th, 2003 Company Industry Jurisdiction
Customer No. 1385 MASTER LEASE AGREEMENT Lessor: TRANSAMERICA BUSINESS CREDIT CORPORATION RIVERWAY II WEST OFFICE TOWER WEST HIGGINS ROSEMONT, ILLINOIS 60018 Co-Lessees: Collectively and ACUSPHERE, INC. individually UNIVERSITY PARK @ MIT referred to...Master Lease Agreement • July 1st, 2003 • Acusphere Inc • Pharmaceutical preparations • Illinois
Contract Type FiledJuly 1st, 2003 Company Industry Jurisdiction
Exhibit 10.34 MASTER SECURITY AGREEMENT dated as of April 16, 2004 ("AGREEMENT") THIS AGREEMENT is between GENERAL ELECTRIC CAPITAL CORPORATION (together with its successors and assigns, if any, "SECURED PARTY") and ACUSPHERE, INC. ("DEBTOR"). Secured...Master Security Agreement • September 15th, 2004 • Acusphere Inc • Pharmaceutical preparations
Contract Type FiledSeptember 15th, 2004 Company Industry
AMENDMENT AND WAIVERInvestors' Rights Agreement • October 16th, 2001 • Acusphere Inc • Pharmaceutical preparations • Massachusetts
Contract Type FiledOctober 16th, 2001 Company Industry Jurisdiction