0001104659-14-058548 Sample Contracts

CONSULTING AGREEMENT
Consulting Agreement • August 8th, 2014 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations • Massachusetts

This Consulting Agreement (the “Agreement”), dated and effective, if at all, as of the Effective Date (as defined in the letter agreement between the Parties dated August 7, 2014), is entered into between Karyopharm Therapeutics Inc., having offices at 85 Wells Avenue, Newton, MA 02459 (the “Company”) and Paul Brannelly, having an address located in Boston, MA (the “Consultant”). The Consultant and Company are referred to in this Agreement individually as a “Party” and collectively as the “Parties”.

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BY HAND DELIVERY August 7, 2014 Mr. Paul Brannelly c/o Karyopharm Therapeutics Inc. Newton, MA 02459 Dear Paul:
Karyopharm Therapeutics Inc. • August 8th, 2014 • Pharmaceutical preparations • Massachusetts

The purpose of this letter agreement is to confirm the terms regarding your separation of employment from Karyopharm Therapeutics Inc. (the “Company”). The Company will provide you with the severance benefits described in paragraph 2 below if you sign and return this letter agreement (the “Agreement”) to me on or before August 28, 2014 and it becomes binding between you and the Company and you sign and return the additional release of claims attached hereto as Exhibit B (the “Additional Release”) to me at the end of the Consulting Period (as defined herein). By timely signing and returning this Agreement and the Additional Release and not revoking them, you will be entering into binding agreements with the Company and will be agreeing to the terms and conditions set forth therein. Therefore, you are advised to consult with an attorney before signing this Agreement and you have been given at least twenty-one (21) days to do so. If you sign this Agreement, you may change your mind and re

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