0001104659-23-096002 Sample Contracts

FORM OF LOCK-UP AGREEMENT August 15, 2023
Lock-Up Agreement • August 28th, 2023 • 5AM Partners VII, LLC • Pharmaceutical preparations

This letter agreement (this “Letter Agreement”) is being delivered to Skye Bioscience, Inc., a Nevada corporation (the “Company”), in accordance with the [Securities Purchase Agreement (the “Purchase Agreement”), dated as of August 15, 2023, by and among the Company and the investors party thereto][Agreement and Plan of Merger and Reorganization (the “Merger Agreement”), dated as of August 15, 2023, by and among the Company, Aquila Merger Sub Inc, a Delaware corporation, and Bird Rock Bio, Inc., a Delaware Corporation]. Capitalized terms used but not otherwise defined in this Letter Agreement shall have the meanings ascribed thereto in the [Purchase Agreement][Merger Agreement].

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EXHIBIT A JOINT FILING AGREEMENT
Joint Filing Agreement • August 28th, 2023 • 5AM Partners VII, LLC • Pharmaceutical preparations

The undersigned hereby agree that a single Schedule 13D (or any amendment thereto) relating to the Common Stock of Skye Bioscience, Inc. shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13D.

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