0001104659-24-109911 Sample Contracts

XORTX Therapeutics Inc. Attention: Dr. Allen Davidoff Ph.D.
Placement Agent Agreement • October 18th, 2024 • XORTX Therapeutics Inc. • Pharmaceutical preparations • New York
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COMMON SHARE PURCHASE WARRANT XORTX THERAPEUTICS INC.
Common Share Purchase Warrant • October 18th, 2024 • XORTX Therapeutics Inc. • Pharmaceutical preparations

THIS COMMON SHARE PURCHASE WARRANT (this “Warrant”) certifies that, for value received, [ ] or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on the date that is the fifth (5th) anniversary of the Initial Exercise Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from XORTX Therapeutics Inc., a British Columbia corporation (the “Company”), up to [ ] common shares of the Company (as subject to adjustment hereunder, the “Warrant Shares”). The purchase price of one Warrant Share under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • October 18th, 2024 • XORTX Therapeutics Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of October 17, 2024, between XORTX Therapeutics Inc., a British Columbia corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

FORM LOCK-UP AGREEMENT
Lock-Up Agreement • October 18th, 2024 • XORTX Therapeutics Inc. • Pharmaceutical preparations

Re: Securities Purchase Agreement, dated as of October 17, 2024 (the “Purchase Agreement”), between XORTX Therapeutics Inc. (the “Company”) and the purchasers signatory thereto (each, a “Purchaser” and, collectively, the “Purchasers”)

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