0001114220-18-000029 Sample Contracts

MASTER MANUFACTURING SERVICES AND SUPPLY AGREEMENT
Master Manufacturing Services and Supply Agreement • February 21st, 2018 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations

This Master Manufacturing Services and Supply Agreement (this “Agreement”) is entered into as of the date of last signature (the “Agreement Date”), by and between Siegfried Evionnaz SA (together with its Affiliates and subsidiaries, “Vendor”), with principal offices located at Route du Simplon 1, 36, 1902 Evionnaz, Switzerland, and Keryx Biopharmaceuticals, Inc. (together with its Affiliates and subsidiaries, “Keryx”), with principal offices located at One Marina Park Drive, 12th Floor, Boston, MA 02210, USA.

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EMPLOYMENT AGREEMENT BETWEEN GREGORY P. MADISON AND
Employment Agreement • February 21st, 2018 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

THIS EMPLOYMENT AGREEMENT (this “Agreement”) is made and entered into this 10th day of March, 2015 by and between Keryx Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), and Gregory P. Madison (“Executive”), to be effective as of the Effective Date, as defined in Section 1.

PRODUCT MANUFACTURE AND SUPPLY AND FACILITY CONSTRUCTION AGREEMENT
Product Manufacture and Supply and Facility Construction Agreement • February 21st, 2018 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations

This product manufacture and supply and facility construction agreement (“Agreement”) is made and entered into on the date of last signature by and between BioVectra Inc., with its registered offices at 11 Aviation Avenue, Charlottetown, PEI, C1E 0A1, Canada (“BioVectra”) and Keryx Biopharmaceuticals, Inc., with its offices at One Marina Park Drive, 12th floor, Boston, Massachusetts, USA, 02210 (“Keryx”).

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