0001130319-09-000171 Sample Contracts

NUCRYST PHARMACEUTICALS CORP. STOCK OPTION AWARD AGREEMENT
Stock Option Award Agreement • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • Alberta

WHEREAS, pursuant to the Company’s 1998 Equity Incentive Plan, as amended (the “Plan”), awards of Options may be granted to persons including executives of subsidiaries of the Company; and

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Telephone: (609)228-8202 Facsimile: (609)228-8220
Telephone • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • Alberta

This letter (“Letter Agreement”) sets out the amendments we agreed to make to the terms of your employment with NUCRYST Pharmaceuticals Corp. (“NUCRYST”) that are set forth in our Offer of Employment dated February 1, 2006 and accepted by you on February 2, 2006, as may be amended from time to time (the “Terms of Employment”).

Our Telephone: (780) 992-5626 Our Telefax: (780) 992-5601
Letter Agreement • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • New York

We refer to the Employment Agreement, dated as of the date hereof (the “Employment Agreement”), between you and NUCRYST Pharmaceuticals Inc. (the “Subsidiary”), a Delaware corporation and a majority owned subsidiary of NUCRYST Pharmaceuticals Corp. (the “Parent”). This letter agreement (this “Letter Agreement”) confirms the Parent’s agreement to be liable for the payment of all amounts due to you under the Employment Agreement. Capitalized terms used and not defined herein have the meanings ascribed to them in the Employment Agreement.

AMENDING AGREEMENT
Amending Agreement • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • Alberta

THIS AGREEMENT, dated March , 2009 and made effective as of May 8, 2008 (the “Effective Date”) between NUCRYST Pharmaceuticals Corp., a corporation incorporated under the laws of the Province of Alberta (the “Company”), and David B. Holtz (the “Participant”).

EMPLOYMENT AGREEMENT
Employment Agreement • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • New York

THIS EMPLOYMENT AGREEMENT (“Agreement”), dated March ___, 2009 and made effective as of January 19, 2009 (the “Effective Date”), by and between NUCRYST PHARMACEUTICALS INC., a Delaware corporation (the “Company”), and DAVID B. HOLTZ (the “Executive”).

Telephone: (609)228-8202 Facsimile: (609)228-8220
Telephone • March 31st, 2009 • NUCRYST Pharmaceuticals Corp. • Surgical & medical instruments & apparatus • Alberta

This letter (“Letter Agreement”) sets out the amendments we agreed to make to the terms of your employment with NUCRYST Pharmaceuticals Corp. (“NUCRYST”) that were set forth in our Revised Offer of Employment dated June 15, 2005 and accepted by you on June 19, 2005, as previously amended by letter agreement dated November 16, 2007 (“Amending Letter”), as subsequently amended (collectively, the “Terms of Employment”).

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