0001144204-05-021602 Sample Contracts

Confidential Treatment Requested. Confidential portions of this document have been redacted and filed separately with the Commission. ***** Confidential material redacted and filed separately with the Commission. RESEARCH AND LICENSE AGREEMENT
Research and License Agreement • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations • London

RESEARCH AND LICENSE AGREEMENT (the “Agreement”) made and entered into as of April 18, 2000 the “Effective Date”), by and between DRK BLUTSPENDEDIENDST BADEN-WURTTENBERG, INSTITUT ULM (the “Licensor”), having an address at Postfach 15 64, U-89005 Ulm, Germany, and XTL BIOPHARMACEUTICALS, LTD. (the “Company”), having an address at Kiryat Weizmann, P.O. Box 370, Rehovot, 76100, Israel.

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Confidential Treatment Requested. Confidential portions of this documents have been redacted and separately filed with the Commission. ***** Confidential material redacted and filed separately with the Commission.
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations

We set out below the amendments to the Agreement (as already amended by Amendment No. 1) and to Amendment No. 1 agreed between Yeda Research and Development Co. Ltd. (“Yeda”) and XTL Biopharmaceuticals, Ltd. (“the Corporation”) following discussions between the parties conducted at the Corporation’s request:

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. LICENSE AGREEMENT
License Agreement • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations • New York

This LICENSE AGREEMENT (this “Agreement”), effective as of June 2, 2004 (the “Effective Date”), is between CUBIST PHARMACEUTICALS, INC., a corporation organized and existing under the laws of Delaware (together with its Affiliates referred to herein as “CUBIST”) and XTL BIOPHARMACEUTICALS LTD., a corporation organized and existing under the laws of Israel (together with its Affiliates referred to herein as “XTL”). XTL and CUBIST are sometimes hereinafter referred to each as a “Party” and collectively as the “Parties.”

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. ***** Confidential material redacted and filed separately with the Commission. LICENSE AGREEMENT
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations • California

Effective as of September 12, 2003 ("Effective Date"), THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, a body having corporate powers under the laws of the State of California ("STANFORD"), and XTL Biopharmaceuticals Ltd., a corporation organized under the laws of Israel having a principal place of business at Kiryat Weizmann, P.O. Box 370, Rehovot, 76100 Israel ("LICENSEE"), agree as follows:

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CONFIDENTIAL TREATMENT REQUESTED. Confidential portions of this document have been redacted and separately filed with the Commission. RESEARCH AND LICENCE AGREEMENT By and Between YEDA RESEARCH AND DEVELOPMENT COMPANY LTD, a company duly incorporated...
Research and Licence Agreement • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations

WHEREAS in the course of research conducted at the Weizmann Institute of Science, Rehovot (hereinafter “the Institute”), ***** (hereinafter “*****”) has developed certain technology constituting the subject matter of the patent applications listed in the attachment hereto marked “A” and constituting an integral part hereof (hereinafter collectively “the Existing Applications” and “the Existing Technology”); and

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. ***** Confidential material redacted and filed separately with the Commission. AGREEMENT
Agreement • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations • California

This Agreement (“Agreement”) is entered into as of September 12, 2003, (the “Effective Date”) by and among XTL Biopharmaceuticals Ltd., a corporation organized under the laws of Israel (“XTL”), Applied Immunogenetics LLC (“AI”), a Delaware limited liability company, ***** and *****.

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Confidential material redacted and filed separately with the Commission. Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission.
XTL Biopharmaceuticals LTD • July 14th, 2005 • Pharmaceutical preparations

Note that confidential treatment has been requested and one (1) page of material has been omitted and filed separately with the Commission.

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. SECOND EXTENSION AGREEMENT Between YEDA RESEARCH AND DEVELOPMENT CO. LTD. of P.O. Box 95, Rehovot 76100, Israel...
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations
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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. ***** Confidential material redacted and filed separately with the Commission.
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations

We set out below the amendment to the Agreement (as already amended by Amendment No.1, Amendment No.2 and Amendment No. 3), following discussions between the parties conducted at the Corporation's request:

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. ***** Confidential material redacted and filed separately with the Commission. January 26, 2003
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations

We set out below the amendments to Amendments No. 1 and No. 2 agreed between Yeda Research and Development Company Ltd. (“Yeda”) and XTL Biopharmaceuticals Ltd. (“the Corporation”) following discussions between the parties conducted at the Corporation’s request (capitalised terms herein having the meanings ascribed thereto in the R&L Agreement, unless otherwise defined herein):

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Confidential Treatment Requested. Confidential portions of this document have been redacted and separately filed with the Commission. THIRD EXTENSION AGREEMENT Between YEDA RESEARCH AND DEVELOPMENT CO. LTD. of P.O. Box 95, Rehovot 76100, Israel...
Confidential Treatment Requested • July 14th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations
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