Exhibit 10.1 RESEARCH AND LICENSE AGREEMENT This License Agreement is entered into as of this 30th day of March, 2006 (the "Restated Effective Date"), by and between Brainstorm Cell Therapeutics Inc.(formerly Golden Hand Resources, Inc.), a company...Research and License Agreement • April 4th, 2006 • Brainstorm Cell Therapeutics Inc • Biological products, (no disgnostic substances)
Contract Type FiledApril 4th, 2006 Company Industry
EXHIBIT 10.19 *** CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT (INDICATED BY ASTERISKS) HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT UNDER 17 C.F.R....Research and License Agreement • March 18th, 2004 • Anadys Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledMarch 18th, 2004 Company Industry Jurisdiction
ARTICLE 1 DEFINITIONSResearch and License Agreement • March 31st, 2003 • Siga Technologies Inc • Pharmaceutical preparations • Delaware
Contract Type FiledMarch 31st, 2003 Company Industry Jurisdiction
CONFIDENTIAL ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 406 of the Securities Act of 1933, as amended. CONFIDENTIAL Execution Copy...Research and License Agreement • May 5th, 2020 • Pennsylvania
Contract Type FiledMay 5th, 2020 JurisdictionThis Amended and Restated Research and License Agreement (“Agreement”) dated as of December 22, 2004, is by and between Centocor, Inc., a Pennsylvania corporation having its principal place of business at 200 Great Valley Parkway, Malvern, Pennsylvania, 19355 (“CENTOCOR”), and MORPHOSYS AG, a German stock corporation with its principal place of business at Lena-Christ-Str. 48, 82152 Martinsried/Planegg, Germany (together with its Affiliates, “MORPHOSYS”), and amends and restates, from and after the date hereof, the Research and License Agreement having an Effective Date of December 29, 2000, as amended by a First Amendment on February 28, 2001, and again by a Second Amendment on April 21, 2003. MORPHOSYS and CENTOCOR are each hereafter referred to individually as a “Party” and together as the “Parties”.
Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • January 14th, 2005 • Icagen Inc • Pharmaceutical preparations • Illinois
Contract Type FiledJanuary 14th, 2005 Company Industry Jurisdiction
EXHIBIT 10.12 AMENDMENT NUMBER 1 TO RESEARCH AND LICENSE AGREEMENT BY AND BETWEEN KOSAN BIOSCIENCES AND R.W. JOHNSON PHARMACEUTICAL RESEARCH INSTITUTE This Amendment dated MAR 17, 2000 is made to the RESEARCH AND LICENSE AGREEMENT (hereinafter called...Research and License Agreement • September 28th, 2000 • Kosan Biosciences Inc • Services-commercial physical & biological research
Contract Type FiledSeptember 28th, 2000 Company Industry
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • August 15th, 2019 • Scopus BioPharma Inc. • Pharmaceutical preparations
Contract Type FiledAugust 15th, 2019 Company IndustryThis Research and License Agreement (“Agreement”) is made in Jerusalem this 8 day of August 2019 (the “Effective Date”), by and between:
THIRD ADDENDUM AGREEMENT Dated: March 23, 2010 BY AND BETWEEN YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. of P.O. Box 95, Rehovot 76100, Israel (hereinafter “Yeda”) and BRAINSWAY. INC. a company duly registered under the laws of the state of Delaware,...Research and License Agreement • January 14th, 2019 • Brainsway Ltd. • Surgical & medical instruments & apparatus
Contract Type FiledJanuary 14th, 2019 Company IndustryWHEREAS The Research defined under the R&L Agreement was extended by two Research extensions, pursuant to the First Addendum Agreement dated: August 19, 2007 and the Second Addendum Agreement, dated: March 5, 2009 (collectively, the “Extensions”); and
RESEARCH AND LICENCE AGREEMENT Entered into on June 2, 2005 Between YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED a company duly registered under the laws of Israel of P O Box 95, Rehovot 76100, Israel (hereinafter, “Yeda”) and BRAINSWAY, INC. a...Research and License Agreement • January 14th, 2019 • Brainsway Ltd. • Surgical & medical instruments & apparatus
Contract Type FiledJanuary 14th, 2019 Company Industry
ContractResearch and License Agreement • September 20th, 2007 • Protalix BioTherapeutics, Inc. • Biological products, (no disgnostic substances)
Contract Type FiledSeptember 20th, 2007 Company IndustryPortions of this exhibit have been omitted pursuant to a request for confidential treatment. The omitted portions, marked by [***], have been separately filed with the Securities and Exchange Commission.
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • June 20th, 2012 • Stemline Therapeutics Inc • Pharmaceutical preparations • Texas
Contract Type FiledJune 20th, 2012 Company Industry JurisdictionThis RESEARCH AND LICENSE AGREEMENT (this “Agreement”), dated as of June 15, 2006 (the “Effective Date”), is made by and between Scott and White Memorial Hospital and Scott, Sherwood and Brindley Foundation for itself and for its Affiliate, Scott & White Clinic (collectively, “S&W”), Texas non-profit corporations, located at 2401 S 31st Street, Temple, Texas 76508; Arthur E. Frankel, M.D.; and Stemline Therapeutics, Inc., a Delaware corporation having a principal place of business located at ***, New York, New York 10128 (“Stemline”).
CONFIDENTIAL TREATMENT REQUESTED UNDER RULE 406 UNDER THE SECURITIES ACT OF 1933, AS AMENDED. […***…] INDICATES OMITTED MATERIAL THAT IS THE SUBJECT OF A CONFIDENTIAL TREATMENT REQUEST FILED SEPARATELY WITH THE COMMISSION. THE OMITTED MATERIAL HAS...Research and License Agreement • April 3rd, 2017 • Zymeworks Inc. • Pharmaceutical preparations • New York
Contract Type FiledApril 3rd, 2017 Company Industry JurisdictionTHIS AMENDED AND RESTATED RESEARCH AND LICENSE AGREEMENT (the “Agreement”), effective as of December , 2014 (the “Restatement Effective Date”), by and between Merck Sharp & Dohme Research GmbH, a corporation organized and existing under the laws of Switzerland, with its principal business office located at Weystrasse 20, 6000 Lucerne 6, Switzerland (“Merck”) and ZYMEWORKS INC., a corporation organized and existing under the laws of Canada, and extraprovincially in British Columbia, having an address at 540-1385 West 8th Avenue, Vancouver, BC, Canada V6H 3V9 (“Zymeworks”). Zymeworks and Merck are each referred to individually as a “Party” and together as the “Parties”.
Execution Copy SECOND AMENDED AND RESTATED RESEARCH AND LICENSE AGREEMENT between FOVEA PHARMACEUTICALS SA and COMBINATORX, INCORPORATED Dated July 22, 2009Research and License Agreement • July 23rd, 2009 • Combinatorx, Inc • Pharmaceutical preparations • New York
Contract Type FiledJuly 23rd, 2009 Company Industry JurisdictionThis Second Amended and Restated Research and License Agreement (the “Agreement”) is dated as of July 22, 2009 (the “Effective Date”) and is between Fovea Pharmaceuticals SA, a company organized and existing under the laws of, France, with an office at Institut de la Vision, 1 rue Moreau 75012 Paris, France (“Fovea”), and CombinatoRx, Incorporated, a company organized and existing under the laws of Delaware, with an office at 245 First Street, Cambridge, MA 02142 (“CombinatoRx”) and amends and restates in its entirety the Amended and Restated Research and License Agreement between Fovea and CombinatoRx (the "Amended and Restated Agreement") dated as of June 12, 2007 (the "Amended and Restated Agreement Effective Date"). Each of Fovea and CombinatoRx are sometimes referred to herein as a “Party” and together as the “Parties.”
Confidential Treatment Requested. Confidential portions of this document have been redacted and filed separately with the Commission. ***** Confidential material redacted and filed separately with the Commission. RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • August 23rd, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations • London
Contract Type FiledAugust 23rd, 2005 Company Industry JurisdictionRESEARCH AND LICENSE AGREEMENT (the “Agreement”) made and entered into as of April 18, 2000 the “Effective Date”), by and between DRK BLUTSPENDEDIENDST BADEN-WURTTENBERG, INSTITUT ULM (the “Licensor”), having an address at Postfach 15 64, U-89005 Ulm, Germany, and XTL BIOPHARMACEUTICALS, LTD. (the “Company”), having an address at Kiryat Weizmann, P.O. Box 370, Rehovot, 76100, Israel.
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • February 26th, 2016 • Todos Medical Ltd. • In vitro & in vivo diagnostic substances
Contract Type FiledFebruary 26th, 2016 Company IndustryThis Agreement is entered into as of this 8th day of April, 2010 (the “Effective Date”), by and between a company to be incorporated under the laws of the State of Israel (the “Company”) (until the Company is incorporated, Crow Technologies 1977 Ltd. Shall be in place of the Company); B.G. Negev Technologies and Applications Ltd., number 510785207, a company formed under the laws of Israel, having a place of business at 1 Henrietta Szold St., Beer Sheva, 84105 (“BG Negev”); and Mor Research Applications Ltd. a company incorporated under the laws of the State of Israel having a place of business at 38 HaBarzel St, Tel Aviv 69710 (“Mor”). BG Negev and Mor shall be referred to hereinafter jointly and severally as “Licensors” and each as a “Licensor”.
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • June 29th, 2015 • Immune Pharmaceuticals Inc • Pharmaceutical preparations
Contract Type FiledJune 29th, 2015 Company IndustryYISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD., of Hi Tech Park, Edmond J. Safra Campus, Givat Ram, Jerusalem 91390, Israel (“Yissum”) of the one part; and
AMENDED RESEARCH AND LICENSE AGREEMENT Execution CopyResearch and License Agreement • June 10th, 2013 • Prosensa Holding B.V. • Pharmaceutical preparations
Contract Type FiledJune 10th, 2013 Company IndustryThis AMENDED RESEARCH AND LICENSE AGREEMENT (the “Agreement”) is made between Prosensa Holding B.V., a company organized under the laws of The Netherlands, having its principal place of business at Leiden at Wassenaarseweg 72 (2333 AL) Leiden (“Prosensa”) and Academisch Ziekenhuis Leiden, acting under the name of Leiden University Medical Center, organized under the laws of The Netherlands, having its principal place of business at Albinusdreef 2, 2333 ZA Leiden (“LUMC”);
CONFIDENTIAL RESEARCH AND LICENSE AGREEMENT between Janssen Biotech, Inc. and Aduro Biotech, Inc. Executed as of October 13, 2014Research and License Agreement • March 11th, 2015 • Aduro Biotech, Inc. • Pharmaceutical preparations • New York
Contract Type FiledMarch 11th, 2015 Company Industry JurisdictionThis Research and License Agreement (this “Agreement”) is made on the 13th day of October 2014 (the “Execution Date”) by and between Aduro Biotech, Inc., a Delaware corporation having a principal place of business at 626 Bancroft Way, 3C, Berkeley, CA 94710 (hereinafter “Aduro”) and Janssen Biotech, Inc., a Pennsylvania corporation, having a place of business at 800 Ridgeview Drive, Horsham, PA 19044 (hereinafter “JBI”). Aduro and JBI may be referred to individually herein as a “Party” or together as the “Parties”.
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • April 19th, 2018 • Eloxx Pharmaceuticals, Inc. • Services-commercial physical & biological research
Contract Type FiledApril 19th, 2018 Company IndustryThis Research and License Agreement is entered into as of this 29th day of August 2013 (the “Effective Date”), by and among Technion Research and Development Foundation Ltd., a company formed under the laws of Israel, having a place of business at the Technion City, Haifa 32000, Israel (“TRDF”) and Eloxx Pharma Ltd., a company formed under the laws of Israel, having a place of business at 14 Shenkar St. Herzelia, Israel (“Licensee”).
RESEARCH AND LICENSE AGREEMENT BETWEEN EYETECH PHARMACEUTICALS, INC. AND ARCHEMIX CORP. Dated April 8, 2004Research and License Agreement • December 19th, 2008 • Nitromed Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 19th, 2008 Company Industry JurisdictionThis Research and License Agreement (the “Agreement”) is made and entered into as of this 8th day of April 2004 (the “Effective Date”) between Archemix Corp., a Delaware corporation with offices at One Hampshire Street, Cambridge, MA 02139 (“ARCHEMIX”), and Eyetech Pharmaceuticals, Inc., a Delaware corporation with offices at 500 Seventh Avenue, 18th Floor, New York, New York 10018 (“EYETECH”).
FIFTH ADDENDUM AGREEMENT (“this Addendum”) Dated: February 22, 2018 (“Effective Date”) BY AND BETWEEN YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. of P.O. Box 95, Rehovot 76100, Israel (hereinafter “Yeda”) and BRAINSWAY, INC. a company duly registered...Research and License Agreement • January 14th, 2019 • Brainsway Ltd. • Surgical & medical instruments & apparatus
Contract Type FiledJanuary 14th, 2019 Company IndustryWHEREAS Yeda and the Company (collectively, “the Parties”) are parties to a Research and License Agreement dated June 2, 2005, as amended by the First Addendum Agreement effective from June 1, 2007; the Second Addendum Agreement effective from August 20, 2008; the Third Addendum effective from March 23, 2010 (“Third Addendum”); the Fourth Addendum Agreement effective from August 1, 2009 (as amended by the First Amendment to the Fourth Addendum dated May 11, 2010) (all of the above, together, “R&L Agreement”); and
Exhibit 10.15 UNIVERSITY OF ARIZONA AND TELIK RESEARCH AND LICENSE AGREEMENT This Agreement, is made as of this 8th day of January, 2001 (the "Effective Date") between the Arizona Board of Regents (ABOR) for The University of Arizona (UNIVERSITY) and...Research and License Agreement • September 20th, 2001 • Telik Inc • Pharmaceutical preparations • Arizona
Contract Type FiledSeptember 20th, 2001 Company Industry Jurisdiction
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • September 2nd, 2020 • Scopus BioPharma Inc. • Pharmaceutical preparations
Contract Type FiledSeptember 2nd, 2020 Company IndustryThis Research and License Agreement (“Agreement”) is made in Jerusalem this 8 day of August 2019 (the “Effective Date”), by and between:
Re: First Amendment of Research and License Agreement, Dated April 15, 2004, by and Among BioLineRX Ltd., Ramot at Tel Aviv University, Ltd and Bar-Ilan Research and Development Company Ltd. the "Agreement")Research and License Agreement • July 1st, 2011 • BioLineRx Ltd. • Pharmaceutical preparations
Contract Type FiledJuly 1st, 2011 Company IndustryYou have brought to our attention the fact that Section 9.1.1 of the Agreement (Licensor Confidential Information) has created a problem with respect to your ability to enter into agreements with potential contractors/collaborators and to attract investors. Specifically, the provision states that your obligations of confidentiality and non-use (other than for the purposes of the Agreement) remain in effect during the term of the agreement, and for five (5) years thereafter. As you have explained to us, potential contractors/collaborators are unwilling to be bound by such confidentiality and non-use obligations with respect to the Confidential Information (as defined in the Agreement) for such undefined term. Therefore, in order to enable you to continue to develop Licensed Product (as defined in the Agreement) and to exercise your rights and fulfill your obligations under the Agreement, we hereby agree to amend the agreement as follows, effective immediately:
RESEARCH AND LICENSE AGREEMENT (HVC)Research and License Agreement • September 21st, 2006 • Rosetta Genomics Ltd. • Pharmaceutical preparations
Contract Type FiledSeptember 21st, 2006 Company IndustryThis agreement (the "Agreement") is made and entered into as of the 30 day of May, 2005 (the "Effective Date") by and between Rosetta Genomics Ltd., a private company registered under the laws of the State of Israel, of 10 Plaut Street, Science Park, Rehovot, Israel ("Rosetta") and Hadasit Medical Research Services and Development Ltd., a private company registered under the laws of the state of Israel, of Hadassah Medical Hospital, POB 12000, Jerusalem, Israel ("Hadasit").
ANDResearch and License Agreement • September 11th, 1997 • Megabios Corp • Services-commercial physical & biological research • Indiana
Contract Type FiledSeptember 11th, 1997 Company Industry Jurisdiction
CONFIDENTIALTREATMENT REQUESTED CONFIDENTIAL PORTIONS OF THIS DOCUMENT HAVE BEEN REDACTED AND HAVE BEEN SEPARATELY FILED WITH THE SECURITIES AND EXCHANGE COMMISSION SECOND AMENDMENT TO THE AMENDED AND RESTATED RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • March 30th, 2015 • MultiVir Inc. • Pharmaceutical preparations • New York
Contract Type FiledMarch 30th, 2015 Company Industry JurisdictionThis Amendment to the Amended and Restated Research and License Agreement, is hereinafter referred to as the “Second Amendment”.
1 EXHIBIT 10.36 RESEARCH AND LICENSE AGREEMENT DATED OCTOBER 26, 2000Research and License Agreement • November 16th, 2000 • Array Biopharma Inc • Services-medical laboratories • Colorado
Contract Type FiledNovember 16th, 2000 Company Industry Jurisdiction
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • July 1st, 2011 • BioLineRx Ltd. • Pharmaceutical preparations
Contract Type FiledJuly 1st, 2011 Company IndustryThis License Agreement is entered into as of this 15 day of April, 2004 (the “Effective Date”), by and among BioLineRx Ltd., a company formed under the laws of Israel, having a place of business at 19 Hartum Street, P.O. Box 45158, Jerusalem, 91450, Israel (“BioLine”); Bar-Ilan Research and Development Company Ltd., a company formed under the laws of Israel, having a place of business at Bar-Ilan University, Ramat Gan, 52900 (“BIRAD”); and Ramot at Tel Aviv University Ltd., a company formed under the laws of Israel, having a place of business at Tel Aviv University in Ramat-Aviv, Tel Aviv 61392, Israel (“Ramot”). BIRAD and Ramot shall be referred to together as the “Licensors”.
Confidential material redacted and filed separately with the Commission. CONFIDENTIAL TREATMENT REQUESTED. Confidential portions of this document have been redacted and separately filed with the Commission. RESEARCH AND LICENCE AGREEMENT By and...Research and License Agreement • August 29th, 2005 • XTL Biopharmaceuticals LTD • Pharmaceutical preparations
Contract Type FiledAugust 29th, 2005 Company IndustryWHEREAS in the course of research conducted at the Weizmann Institute of Science, Rehovot (hereinafter “the Institute”), ***** (hereinafter “*****”) has developed certain technology constituting the subject matter of the patent applications listed in the attachment hereto marked “A” and constituting an integral part hereof (hereinafter collectively “the Existing Applications” and “the Existing Technology”); and
AUTOGEN Pty Ltd and LIPHA S.A.Research and License Agreement • June 23rd, 2005 • Chemgenex Pharmaceuticals LTD • American depositary receipts
Contract Type FiledJune 23rd, 2005 Company Industry
Certain portions of this exhibit have been omitted based upon a request for confidential treatment. Omitted portions have been separately filed with the Securities and Exchange Commission. RESEARCH AND LICENSE AGREEMENT This Agreement dated 23rd day...Research and License Agreement • November 5th, 1997 • Osiris Therapeutics Inc • Services-medical laboratories • Maryland
Contract Type FiledNovember 5th, 1997 Company Industry Jurisdiction
EXHIBIT 10.41 CONFIDENTIAL TREATMENT AMENDMENT NUMBER 3 TO RESEARCH AND LICENSE AGREEMENT BY AND BETWEEN MICROCIDE PHARMACEUTICALS, INC., ORTHO PHARMACEUTICAL CORPORATION AND R.W. JOHNSON PHARMACEUTICAL RESEARCH INSTITUTE This Amendment Number 3...Research and License Agreement • March 29th, 2002 • Essential Therapeutics Inc • Pharmaceutical preparations
Contract Type FiledMarch 29th, 2002 Company Industry
AMENDMENT AGREEMENTResearch and License Agreement • July 1st, 2011 • BioLineRx Ltd. • Pharmaceutical preparations
Contract Type FiledJuly 1st, 2011 Company IndustryTHIS AMENDMENT AGREEMENT, dated as of the 7th day of March, 2006, (the "Effective Date"), is entered into by and between BioLineRx Ltd. ("BioLine"), Bar-Ilan Research and Development Company Ltd. ("BIRAD") and Ramot at Tel Aviv University Ltd. ("Ramot", and together with BIRAD, the "Licensors").
RESEARCH AND LICENSE AGREEMENTResearch and License Agreement • November 4th, 2015 • Xencor Inc • Pharmaceutical preparations • California
Contract Type FiledNovember 4th, 2015 Company Industry JurisdictionThis Research and License Agreement (the “Agreement”) is entered into as of September 15, 2015 (the “Effective Date”), by and between Xencor, Inc., a corporation organized under the laws of the State of Delaware (“Xencor”), having an address of 111 West Lemon Avenue, Monrovia, California 91016, and Amgen Inc., a corporation organized under the laws of the State of Delaware (“Amgen”), having an address of One Amgen Center Drive, Thousand Oaks, California 91320.