0001144204-14-021669 Sample Contracts

LICENSE AGREEMENT
License Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories • Arkansas

THIS LICENSE AGREEMENT (this “AGREEMENT”) is made by and between the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences, a public institution of higher education having principal offices at 2404 North University Avenue, Little Rock, Arkansas 72207, United States of America (hereinafter “UNIVERSITY”), and Myeloma Health LLC, a Delaware limited liability company having a principal office at 667 Madison Avenue, 14th Floor, New York, New York 10065 (hereinafter “LICENSEE”), as of the EFFECTIVE DATE (as later defined herein).

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AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories • New York

This Amended and Restated Employment Agreement (this “Agreement”) is entered into effective as of _________, 2014 (the “Effective Date”) between Signal Genetics, Inc. (the “Company” or “SG”) and Samuel D. Riccitelli (the “Executive”). (Executive and the Company are referenced collectively herein as the “Parties.”)

LEASE AGREEMENT
Lease Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories • Arkansas

This agreement of Lease made and entered into by and between the Board of Trustees of the University of Arkansas for the University of Arkansas for Medical Sciences (hereinafter referred to as “UNIVERSITY”) and Myeloma Health LLC, a limited liability corporation organized and existing under the laws of the State of Delaware ( hereinafter referred to as “CLIENT”).

EMPLOYMENT AGREEMENT
Employment Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories • New York

This Employment Agreement (the “Agreement”) is entered into effective as of October 31, 2012 (the “Effective Date”) between Signal Genetics, LLC (the “Company” or “SG”) and Samuel D. Riccitelli (“Executive”). (Executive and the Company are referenced collectively herein as the “Parties.”)

University of Arkansas for Medical Sciences 4301 West Markham Street #632 Little Rock, AR 72205-7199 WBowes@uams.edu Phone 501 686-5671 Fax 501 686-8137 William R. Bowes, CFO Vice Chancellor for Finance & Administration
Reference Laboratory Services Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories

The purpose of this letter agreement is to state the terms under which the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences ("UAMS") and Signal Genetics, LLC will act regarding the "Reference Laboratory Services Agreement" and the "Reference Laboratory Services Agreement for Research Specimens" both effective on March 21, 2011, and amendment. The agreements and amendment are attached for your reference. These two agreements expire on March 20, 2014. The parties have not provided notice that the agreements will be renewed per the agreements. UAMS intends to continue receiving services from Signal Genetics, LLC, and believes it is in its best interest to continue receiving the laboratory services in accordance with the agreements for the next sixty (60) days during which time new and current agreements can be prepared and executed between the parties.

EXCHANGE AGREEMENT
Exchange Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories • Delaware

This Exchange Agreement (this “Agreement”) is dated as of _______, 2014, by and among SIGNAL GENETICS LLC, a Delaware limited liability company (the “Company”), LeBow Alpha LLLP, a Delaware limited liability limited partnership (“Alpha”), LeBow Gamma Limited Partnership, a Delaware limited partnership (“Gamma”), BSL Capital, Inc., a Nevada corporation (“BSL” and, together with Alpha, Gamma and BSL, the “Lenders”), and BENNETT S. LEBOW, an individual (“LeBow” and, together with the Lenders, the “LeBow Parties”).

SIGNAL GENETICS, INC. RESTRICTED STOCK UNIT GRANT AGREEMENT UNDER THE 2014 STOCK INCENTIVE PLAN
Restricted Stock Unit Grant Agreement • April 9th, 2014 • Signal Genetics LLC • Services-medical laboratories

This Restricted Stock Unit Grant Agreement (this “Grant Agreement”), is made and entered into as of the date of grant set forth below (the “Date of Grant”) by and between Signal Genetics, Inc., a Delaware corporation (the “Company”), and the participant named below (the “Participant”). Capitalized terms not defined herein have the meanings ascribed to them in the Signal Genetics, Inc. 2014 Stock Incentive Plan (the “Plan”). Where the context permits, references to the Company include any successor to the Company.

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