0001156973-07-000341 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations • New York
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Change Order Number 4
Change Order • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations

IN WITNESS WHEREOF, the parties hereto have executed this Change Order by their duly authorised representatives on the date(s) written below.

Agreement
Confidentiality Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations

This Agreement made this 15th day of November 2005 by and between Nisshin Pharma Inc., a Japanese corporation having its principal office at 25, Kanda-Nishikicho 1-chome, Chiyoda-ku, Tokyo, Japan (hereinafter referred to as “Nisshin”) and Amarin Pharmaceuticals Ireland Limited, an Irish Company (which is wholly owned by Amarin Corporation plc) having its principal office at 50 Pembroke Road, Dublin 2, (hereinafter referred to as “Amarin”) and Amarin Neuroscience limited, a Scottish company having its principle office at King Park House, Laurelhill Business Park, Polmaise Road, Stirling, UK,FK7 9JQ, in connection with the Agreement made on the 27th October 1999 between Nisshin Flour Milling Co., Ltd., a Japanese corporation, the parent company of Nisshin, and Laxdale Limited, a Scottish company now known as Amarin Neuroscience Limited due to the corporate take-over closed on the 8th October 2004 by Amarin Corporation plc, which was assigned on the 2nd July 2001 by Nisshin Flour Milling

DATED 17 MAY 2006 AND ASSIGNMENT AGREEMENT MATHESON ORMSBY PRENTICE Dublin 2 Ireland
Assignment Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations • England
Contract
Clinical Trial Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations

Certain portions of this Exhibit have been omitted pursuant to a request for “Confidential Treatment” under Rule 24b-2 of the Securities and Exchange Commission. Such portions have been redacted and bracketed in the request and appear as [*] in the text of this Exhibit. The omitted confidential information has been filed with the Securities and Exchange Commission.

MASTER SERVICES AGREEMENT
Master Services Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations • England

BETWEEN ICON Clinical Research (UK) Limited doing business as ICON Development Solutions (hereinafter called “ICON”) of 2 Globeside, Globeside Business Park, Marlow, Bucks SL7 1HZ, UK

Change Order Number 3
Change Order • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations
October 26, 2006
Worldwide Exclusive License Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations
STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations • New York

This Stock Purchase Agreement (the “Agreement”) is made as of the date set forth below between Amarin Corporation plc, a public limited company registered in England and Wales (the “Company”), and the Investors listed on Exhibit A.

PURCHASE AGREEMENT
Purchase Agreement • March 5th, 2007 • Amarin Corp Plc\uk • Pharmaceutical preparations • New York
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