0001178913-13-002903 Sample Contracts

WORK AUTHORISATION Reference: WA002 (PBT2-204)
Work Authorisation • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations

This Work Authorisation is between Prana Biotechnology Limited of Level 2, 369 Royal Parade, Parkville, VIC 3052, Australia (hereinafter “Customer”) and INCResearch Australia Pty Limited ACN 080 425 387 & ABN 67 080 425 387, 124 Lipson Street, Port Adelaide 5015 SA (hereinafter “INC”) and relates to the Master Services Agreement dated 28th September 2011, (the “Master Agreement”). Pursuant to the Master Agreement, INC has agreed to provide certain services in accordance with written work authorisations, such as this one, entered into from time-to-time describing such services.

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FIFTH RESEARCH FUNDING AND INTELLECTUAL PROPERTY ASSIGNMENT AGREEMENT BETWEEN UNIVERSITY OF MELBOURNE AND PRANA BIOTECHNOLOGY LTD (ABN 37 080 699 065)
Research Funding and Intellectual Property Assignment Agreement • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations • Victoria

THE UNIVERSITY OF MELBOURNE [ABN 84 002 705 224] of Parkville, Victoria 3010, a body politic and corporate pursuant to the provisions of the University of Melbourne Act 2009 (Vic) (University)

MANUFACTURING SERVICES AGREEMENT FOR PBT2 HCI SUPPLY
Manufacturing Services Agreement • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations • London

This MANUFACTURING SERVICES AGREEMENT (hereinafter called “Agreement”) is made on this 19 day of August, 2013 by and between Prana Biotechnology Ltd ACN 080 699 065 (“Prana”), a company incorporated in Australia whose registered office and principal place of business is at Level 2,369 Royal Parade, Parkville Victoria 3052 and Dr. Reddy’s Laboratories Limited (“Dr. Reddy’s”), a company incorporated and existing under the laws of India, having its principal place of business at # 8-2-337, Road No.3, Banjara Hills, Hyderabad 500 034, Andhra Pradesh, India.

WORK ORDER INC Research Project # 1000504 Protocol # PBT2-203
Work Order • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations

This Work Order (hereinafter “Work Order”) is between Prana Biotechnology Limited (hereinafter “Sponsor”) with principal offices located at Level 2, 369 Royal Parade, Parkville VIC 3052 Australia and INCResearch Australia Pty Limited, together with its parent company, subsidiaries and legal affiliates (hereinafter “INC Research”) with offices located at 124 Lipson Street, Port Adelaide SA 5015 Australia and relates to the Master Services Agreement effectively dated 22nd September 2011 which expressly incorporates this Work Order hereto by reference into the Master Services Agreement. Pursuant to the Master Services Agreement, INC Research has agreed to perform certain services in accordance with written work orders, such as this one, entered into from time to time describing such services.

MASTER SERVICES AGREEMENT FOR PROVISION OF CLINICAL RESEARCH SERVICES Between INCResearch Australia Pty Limited (ABN 67 080 425 387) of 124 Lipson Street, Port Adelaide, South Australia 5015, Australia (INC) And Prana Biotechnology Limited (ABN...
Master Services Agreement • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations • Victoria

INTRODUCTION The Customer has requested and INC has agreed to provide the Services to the Customer. In consideration for the provision of the Services the Customer has agreed to pay INC the Services Fee. OPERATIVE CLAUSES PART 1 – PRELIMINARY 1. Definitions In this Agreement: 1.1 “Address” means the addresses of the Customer and INC specified in Item 3 of Schedule 1, or such other address as may be notified; 1.2 “Affiliates” means a related body corporate within the meaning of the Corporations Act (Cth) 2001; 1.3 “Business Day” means any day except a Saturday or a Sunday or other public holiday in South Australia; 1.4 “Business Records” means a record of: 1.4.1 the functions, decisions and meetings of the board of the Customer; 1.4.2 the conduct of the Customer’s Operations; 1.4.3 the outgoings in respect of the Customer’s Operations; 1.4.4 all marketing, advertising or promotions conducted by the Customer; and 1.4.5 all other information kept in respect of the Customer’s Operations as

Amendment 14 to Agreement dated 26th Dec’08 signed by and between
Amendment 14 to Agreement Dated 26th Dec’08 • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations

This amendment will include the following additional and amended clauses in the above mentioned Agreement (plus amendments) and will be in effect from 18 September 2012.

WORK ORDER
Work Order • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations

This Work Order (hereinafter “Work Order”) is between Prana Biotechnology Limited (hereinafter “Sponsor”) with principal offices located at Level 2, 369 Royal Parade, Parkville VIC 3052 Australia and INCResearch Australia Pty Limited, together with its parent company, subsidiaries and legal affiliates (hereinafter “INC Research”) with offices located at 124 Lipson Street, Port Adelaide SA 5015 Australia and relates to the Master Services Agreement effectively dated 22nd September 2011 which expressly incorporates this Work Order hereto by reference into the Master Services Agreement. Pursuant to the Master Services Agreement, INC Research has agreed to perform certain services in accordance with written work orders, such as this one, entered into from time to time describing such services.

Prana Biotechnology Limited Level 2, 369 Royal Parade, Parkville
Letter Agreement for Clinical Trial Services • October 22nd, 2013 • Prana Biotechnology LTD • Pharmaceutical preparations
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