0001188112-12-000462 Sample Contracts

EMPLOYMENT AGREEMENT
Employment Agreement • February 24th, 2012 • Arqule Inc • Pharmaceutical preparations

This Employment Agreement (the “Agreement”) dated as of June 17, 2008 (the “Execution Date”) is made by and between ArQule, Inc., a Delaware corporation (the “Company”) with its principal offices at 19 Presidential Way, Woburn, Massachusetts 01801, and Brian Schwartz (“Executive”) whose current principal residential address is 18 October Hill Road, Woodbridge, Connecticut 06525.

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AMENDMENT TO EMPLOYMENT AGREEMENT
Employment Agreement • February 24th, 2012 • Arqule Inc • Pharmaceutical preparations • Massachusetts

This Amendment to Employment Agreement (“Amendment”) is entered into by and between ArQule, Inc., a Delaware corporation (the “Company”) with its principal offices at 19 Presidential Way, Woburn, Massachusetts 01801, and Dr. Brian Schwartz, the Company’s Chief Medical Officer (“Executive”). The purpose of this Amendment is to amend the Employment Agreement dated as of June 17, 2008, between the Company and Executive (the “Agreement”). This Amendment shall be effective as of the date of execution set forth below (the “Effective Date”). Capitalized terms used but not defined in this Amendment shall have the meanings ascribed to them in the Agreement. In consideration of the mutual covenants and agreements contained herein and for other good and valuable consideration, the receipt, adequacy and sufficiency of which are hereby acknowledged, the Company and Executive (collectively, the “Parties”) hereby agree as follows:

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