Arqule Inc Sample Contracts

OPTION AGREEMENT
Option Agreement • October 15th, 1996 • Arqule Inc • Pharmaceutical preparations • New York
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ARQULE, INC.
Underwriting Agreement • April 3rd, 1997 • Arqule Inc • Pharmaceutical preparations • California
RECITALS
Termination Agreement • March 12th, 2004 • Arqule Inc • Pharmaceutical preparations
ArQule, Inc. (a Delaware corporation) 9,250,000 Shares of Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • June 25th, 2019 • Arqule Inc • Pharmaceutical preparations • New York

ArQule, Inc., a Delaware corporation (the “Company”), confirms its agreement with SVB Leerink LLC (“SVB Leerink”) and RBC Capital Markets, LLC (“RBC Capital Markets”) and each of the other Underwriters named in Schedule A hereto (collectively, the “Underwriters,” which term shall also include any underwriter substituted as hereinafter provided in Section 10 hereof), for which SVB Leerink and RBC Capital Markets are acting as representatives (in such capacity, the “Representatives”), with respect to (i) the sale by the Company and the purchase by the Underwriters, acting severally and not jointly, of the respective numbers of shares of common stock, par value $.01 per share, of the Company (“Common Stock”) set forth in Schedule A hereto and (ii) the grant by the Company to the Underwriters, acting severally and not jointly, of the option described in Section 2(b) hereof to purchase all or any part of 1,387,500 additional shares of Common Stock. The aforesaid 9,250,000 shares of Common S

Exhibit 1.1 ----------- JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13G/A, dated February 14, 2003, (the "Schedule 13G/A"), with respect to the Common Stock, $.01 par value, of ArQule, Inc. is filed on behalf of...
Joint Filing Agreement • February 14th, 2003 • Arqule Inc • Pharmaceutical preparations

The undersigned hereby agree that the Statement on Schedule 13G/A, dated February 14, 2003, (the "Schedule 13G/A"), with respect to the Common Stock, $.01 par value, of ArQule, Inc. is filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities and Exchange Act of 1934, as amended, and that this Agreement shall be included as an Exhibit to this Schedule 13G/A. Each of the undersigned agrees to be responsible for the timely filing of the Schedule 13G/A, and for the completeness and accuracy of the information concerning itself contained therein. This Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.

1 COMMON STOCK PURCHASE AGREEMENT
Common Stock Purchase Agreement • August 12th, 1997 • Arqule Inc • Pharmaceutical preparations • Delaware
SUBLEASE
Sublease • December 21st, 1999 • Arqule Inc • Pharmaceutical preparations • Massachusetts
LEASE
Lease • May 6th, 2005 • Arqule Inc • Pharmaceutical preparations • Massachusetts
BY AND AMONG ARQULE, INC.
Merger Agreement • February 1st, 2001 • Arqule Inc • Pharmaceutical preparations • Delaware
Exhibit 10.21 AMENDED AND RESTATED LEASE by and between ARE-MA Region No. 20, LLC
Lease Agreement • August 5th, 2005 • Arqule Inc • Pharmaceutical preparations • Massachusetts
INTRODUCTION
Strategic Alliance Agreement • May 7th, 2004 • Arqule Inc • Pharmaceutical preparations • Delaware
R E C I T A L S
Consulting Agreement • August 9th, 2002 • Arqule Inc • Pharmaceutical preparations • Massachusetts
LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • January 10th, 2017 • Arqule Inc • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of January 6, 2017 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender (each a “Lender” and collectively, the “Lenders”), and ARQULE, INC., a Delaware corporation, with offices located at One Wall Street, Burlington, MA 01803 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

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ARQULE, INC. 7,000,000 Shares Common Stock ($0.01 par value per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • June 15th, 2007 • Arqule Inc • Pharmaceutical preparations • New York

Each of the undersigned, Stephen A. Hill, President and Chief Executive Officer of ArQule, Inc., a Delaware corporation (the “Company”), and Richard H. Woodrich, Acting Chief Financial Officer of the Company, on behalf of the Company, does hereby certify pursuant to Section 6(j) of that certain Underwriting Agreement dated June 13, 2007 (the “Underwriting Agreement”) between the Company and, on behalf of the several Underwriters named therein, UBS Securities LLC, CIBC World Markets Corp, Leerink Swann & Co., Inc., Fortis Securities LLC and Rodman & Renshaw, LLC, that as of [date]:

ARQULE, INC.
Underwriting Agreement • March 7th, 1997 • Arqule Inc • Pharmaceutical preparations • California
EXHIBIT 10.16 RESEARCH AND DEVELOPMENT AGREEMENT
Research and Development Agreement • March 12th, 2004 • Arqule Inc • Pharmaceutical preparations • Massachusetts
RECITALS
Promissory Note Amendment • November 14th, 1997 • Arqule Inc • Pharmaceutical preparations
ArQule, Inc. Common Stock ($0.01 par value per share) Capital on Demand™ Sales Agreement
Capital on Demand Sales Agreement • October 26th, 2016 • Arqule Inc • Pharmaceutical preparations • New York
EXHIBIT 10.1 RESEARCH COLLABORATION AND LICENSE AGREEMENT
Research Collaboration and License Agreement • August 25th, 1998 • Arqule Inc • Pharmaceutical preparations • Delaware
Contract
Warrant Agreement • February 22nd, 2018 • Arqule Inc • Pharmaceutical preparations • California

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

ARQULE, INC. 200 Boston Avenue Suite 1000 Medford, MA 02155
Term Loan Agreement • May 11th, 1999 • Arqule Inc • Pharmaceutical preparations • Massachusetts
RECITALS
Lease • March 22nd, 2001 • Arqule Inc • Pharmaceutical preparations
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