ARQULE, INC. (a Delaware corporation) 7,150,000 Shares of Common Stock UNDERWRITING AGREEMENTUnderwriting Agreement • April 12th, 2012 • Arqule Inc • Pharmaceutical preparations • New York
ArQule, Inc., a Delaware corporation (the “Company”), confirms its agreement with Citigroup Global Markets Inc. (“Citigroup”) and Leerink Swann LLC (“Leerink Swann”) and each of the other Underwriters named in Schedule A hereto (collectively, the “Underwriters,” which term shall also include any underwriter substituted as hereinafter provided in Section 10 hereof), for whom Citigroup and Leerink Swann are acting as representatives (in such capacity, the “Representatives”), with respect to (i) the issue and sale by the Company and the purchase by the Underwriters, acting severally and not jointly, of the respective numbers of shares of Common Stock, par value $0.01 per share, of the Company (“Common Stock”) set forth in said Schedule A, and (ii) the grant by the Company to the Underwriters, severally and not jointly, of the option described in Section 2(b) hereof to purchase all or any part of 1,072,500 additional shares of Common Stock. The aforesaid 7,150,000 shares of Common Stock (t
